释义 |
- References
- Further reading
{{Infobox_gene}}Kin of IRRE-like protein 2, also known as NEPH3, is a protein that in humans is encoded by the KIRREL2 gene.[1][2][3] It is primarily expressed in β cells of the pancreatic islets.[1]KIRREL2 is a member of the NEPH protein family, which includes NEPH1 (KIRREL) and NEPH2 (KIRREL3). NEPH proteins bind the References1. ^1 {{cite journal |vauthors=Sun C, Kilburn D, Lukashin A, Crowell T, Gardner H, Brundiers R, Diefenbach B, Carulli JP | title = Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in beta cells of the pancreatic islets | journal = Genomics | volume = 82 | issue = 2 | pages = 130–42 |date=Jul 2003 | pmid = 12837264 | pmc = | doi =10.1016/S0888-7543(03)00110-1 }} 2. ^{{cite journal |vauthors=Ihalmo P, Palmen T, Ahola H, Valtonen E, Holthofer H | title = Filtrin is a novel member of nephrin-like proteins | journal = Biochem Biophys Res Commun | volume = 300 | issue = 2 | pages = 364–70 |date=Dec 2002 | pmid = 12504092 | pmc = | doi =10.1016/S0006-291X(02)02854-1 }} 3. ^{{cite web | title = Entrez Gene: KIRREL2 kin of IRRE like 2 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84063| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
- {{cite journal |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
- {{cite journal |vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 | pmc=2286551 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Rinta-Valkama J, Aaltonen P, Lassila M, etal |title=Densin and filtrin in the pancreas and in the kidney, targets for humoral autoimmunity in patients with type 1 diabetes. |journal=Diabetes Metab. Res. Rev. |volume=23 |issue= 2 |pages= 119–26 |year= 2007 |pmid= 16741999 |doi= 10.1002/dmrr.655 }}
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