Kníř/Knirsch is a surname of Czech origin. The Czech "Kníř" was transposed to German as "Knirsch" or "Knirsh". The etymology can be traced to the Czech word "chmýří" (English translation: "fluff") being explained as a person with fine hair.

People with this surname include:

• Eduard Knirsch (? - 1955), an Austrian doctor and entomologist
• Hans Knirsch (1877–1933), a Moravian German activist

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