KOTV may refer to:

• KOTV-DT, a television station (virtual channel 6) licensed to Tulsa, Oklahoma, United States
• KOTV Boxing, a weekly television programme on Channel 4 in the United Kingdom

• Tetramicra (orchid)
• Tetraminos
• Tetramminecopper(II) sulphate
• Tetramoera isogramma
• Tetramorium hispidum
• Tetramorium plumosum
• Tetramorium renae
• Tetramorium sepultum
• Tetramorium tsushimae
• Tetramune
• Tetranary compound
• Tetranectin
• Tetraneura
• Tetraneura ulmi
• Tetranitrogen tetrasulfide
• Tetranitrogen tetrasulphide
• Tetranonagesimal
• Tetranthella
• Tetranychoidea
• Tetraodon alboreticulatus
• Tetraodon barbatus
• Tetraodon biocellatus
• Tetraodon erythrotaenia
• Tetraodon kretamensis
• Tetraodon nigroviridis