| 词条 | KT5720 |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 429900033 | ImageFile=KT 5720.svg | ImageSize=150px | IUPACName=(5R,6S,8S)-Hexyl 6-hydroxy-5-methyl-13-oxo-6,7,8,13,14,15-hexahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-6-carboxylate | OtherNames=KT 5720 |Section1={{Chembox Identifiers | CASNo=108068-98-0 | CASNo_Ref = {{cascite|correct|CAS}} | UNII_Ref = {{fdacite|changed|FDA}} | UNII = 58HV29I28S | PubChem = 454202 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 399960 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 85085 | SMILES = CCCCCCOC(=O)[C@@]1(C[C@H]2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)[C@@]1(O2)C)CNC6=O)O | InChI = 1/C32H31N3O5/c1-3-4-5-10-15-39-30(37)32(38)16-23-34-21-13-8-6-11-18(21)25-26-20(17-33-29(26)36)24-19-12-7-9-14-22(19)35(28(24)27(25)34)31(32,2)40-23/h6-9,11-14,23,38H,3-5,10,15-17H2,1-2H3,(H,33,36)/t23-,31+,32+/m0/s1 | InChIKey = ZHEHVZXPFVXKEY-RUAOOFDTBS | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C32H31N3O5/c1-3-4-5-10-15-39-30(37)32(38)16-23-34-21-13-8-6-11-18(21)25-26-20(17-33-29(26)36)24-19-12-7-9-14-22(19)35(28(24)27(25)34)31(32,2)40-23/h6-9,11-14,23,38H,3-5,10,15-17H2,1-2H3,(H,33,36)/t23-,31+,32+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = ZHEHVZXPFVXKEY-RUAOOFDTSA-N |Section2={{Chembox Properties | C=32|H=31|N=3|O=5 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt= }} KT5720 is a kinase inhibitor with specificity towards protein kinase A.[1] It is a semi-synthetic derivative of K252a[2] and analog of staurosporine. References1. ^{{cite journal |last1=Makarevich |first1=A. V. |last2=Sirotkin |first2=A. V. |last3=Rafay |first3=J. |title=Comparison of Effects of Protein Kinase A, Mitogen-activated Protein Kinase, and Cyclin-dependent Kinase Blockers on Rabbit Ovarian Granulosa Cell Functions |journal=Hormone and Metabolic Research |volume=42 |issue=13 |pages=936–43 |year=2010 |pmid=20972940 |doi=10.1055/s-0030-1267226}} {{DEFAULTSORT:Kt5720}}{{Biochem-stub}}2. ^{{PubChem|3844}} 3 : Alkaloids|Protein kinase inhibitors|Indolocarbazoles |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。