| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}Ligand-dependent corepressor is a protein that in humans is encoded by the LCOR gene.[1][2][3] Function LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.[3] References1. ^{{cite journal |vauthors=Fernandes I, Bastien Y, Wai T, Nygard K, Lin R, Cormier O, Lee HS, Eng F, Bertos NR, Pelletier N, Mader S, Han VK, Yang XJ, White JH | title = Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms | journal = Mol Cell | volume = 11 | issue = 1 | pages = 139–50 |date=Jan 2003 | pmid = 12535528 | pmc = | doi =10.1016/S1097-2765(03)00014-5 }}
2. ^{{cite journal |vauthors=White JH, Fernandes I, Mader S, Yang XJ | title = Corepressor recruitment by agonist-bound nuclear receptors | journal = Vitam Horm | volume = 68 | issue = | pages = 123–43 |date=Jun 2004 | pmid = 15193453 | pmc = | doi = 10.1016/S0083-6729(04)68004-6 }}
3. ^1 {{cite web | title = Entrez Gene: LCOR ligand dependent nuclear receptor corepressor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84458| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Nagase T, Nakayama M, Nakajima D, etal |title=Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=8 |issue= 2 |pages= 85–95 |year= 2001 |pmid= 11347906 |doi=10.1093/dnares/8.2.85 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Kunieda T, Park JM, Takeuchi H, Kubo T |title=Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1). |journal=FEBS Lett. |volume=535 |issue= 1–3 |pages= 61–5 |year= 2003 |pmid= 12560079 |doi=10.1016/S0014-5793(02)03858-9 }}
- {{cite journal |vauthors=Shi Y, Sawada J, Sui G, etal |title=Coordinated histone modifications mediated by a CtBP co-repressor complex |journal=Nature |volume=422 |issue= 6933 |pages= 735–8 |year= 2003 |pmid= 12700765 |doi= 10.1038/nature01550 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Deloukas P, Earthrowl ME, Grafham DV, etal |title=The DNA sequence and comparative analysis of human chromosome 10 |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
{{refend}}{{PDB Gallery|geneid=84458}}{{Transcription coregulators}}{{gene-10-stub}} 1 : Transcription coregulators |