词条 | Leptosidin |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 423598730 | Name = Leptosidin | ImageFile = Leptosidin.svg | IUPACName = (2Z)-2-[(3,4-Dihydroxyphenyl)methylidene]-6-hydroxy-7-methoxy-1-benzofuran-3-one | OtherNames = |Section1={{Chembox Identifiers | CASNo = 486-24-8 | CASNo_Ref = {{cascite|changed|??}} | CASNoOther = | PubChem = 5281257 | SMILES = COc(c(O)3)c(o1)c(cc3)c(=O)c(=Cc(c2)cc(O)c(O)c2)1 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 4444669 | InChI = 1/C16H12O6/c1-21-16-11(18)5-3-9-14(20)13(22-15(9)16)7-8-2-4-10(17)12(19)6-8/h2-7,17-19H,1H3/b13-7- | InChIKey = PFRGTMTYWMVLMU-QPEQYQDCBV | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C16H12O6/c1-21-16-11(18)5-3-9-14(20)13(22-15(9)16)7-8-2-4-10(17)12(19)6-8/h2-7,17-19H,1H3/b13-7- | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = PFRGTMTYWMVLMU-QPEQYQDCSA-N | RTECS = | MeSHName = | ChEBI = | KEGG_Ref = {{keggcite|changed|kegg}} | KEGG = C08651 |Section2={{Chembox Properties | C=16 | H=12 | O=6 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }}Leptosidin was the first aurone to be isolated in Coreopsis grandiflora by Geissman T.A. and Heaton C.D. in 1943.[1] Leptosidin blocks the active residues of PRKACA.[2] References1. ^Leptosidin on metabolomics.jp {{aurone}}{{Natural-phenol-stub}}2. ^{{cite journal|title=Docking and molecular dynamics simulations studies of human protein kinase catalytic subunit alpha with antagonist|journal=Journal of Clinical and Scientific Research|pages=15–23|doi=10.15380/2277-5706.JCSR.12.005|year=2012|last1=s|first1=Sandeep|last2=v|first2=Priyadarshini|last3=d|first3=Pradhan|last4=m|first4=Munikumar|last5=a|first5=Umamaheswari}} 3 : Aurones|Catechols|Phenol ethers |
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