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词条 Leptosidin
释义

  1. References

{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 423598730
| Name = Leptosidin
| ImageFile = Leptosidin.svg
| IUPACName = (2Z)-2-[(3,4-Dihydroxyphenyl)methylidene]-6-hydroxy-7-methoxy-1-benzofuran-3-one
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo = 486-24-8
| CASNo_Ref = {{cascite|changed|??}}
| CASNoOther =
| PubChem = 5281257
| SMILES = COc(c(O)3)c(o1)c(cc3)c(=O)c(=Cc(c2)cc(O)c(O)c2)1
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4444669
| InChI = 1/C16H12O6/c1-21-16-11(18)5-3-9-14(20)13(22-15(9)16)7-8-2-4-10(17)12(19)6-8/h2-7,17-19H,1H3/b13-7-
| InChIKey = PFRGTMTYWMVLMU-QPEQYQDCBV
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C16H12O6/c1-21-16-11(18)5-3-9-14(20)13(22-15(9)16)7-8-2-4-10(17)12(19)6-8/h2-7,17-19H,1H3/b13-7-
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = PFRGTMTYWMVLMU-QPEQYQDCSA-N
| RTECS =
| MeSHName =
| ChEBI =
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = C08651
|Section2={{Chembox Properties
| C=16 | H=12 | O=6
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
}}Leptosidin was the first aurone to be isolated in Coreopsis grandiflora by Geissman T.A. and Heaton C.D. in 1943.[1] Leptosidin blocks the active residues of PRKACA.[2]

References

1. ^Leptosidin on metabolomics.jp
2. ^{{cite journal|title=Docking and molecular dynamics simulations studies of human protein kinase catalytic subunit alpha with antagonist|journal=Journal of Clinical and Scientific Research|pages=15–23|doi=10.15380/2277-5706.JCSR.12.005|year=2012|last1=s|first1=Sandeep|last2=v|first2=Priyadarshini|last3=d|first3=Pradhan|last4=m|first4=Munikumar|last5=a|first5=Umamaheswari}}
{{aurone}}{{Natural-phenol-stub}}

3 : Aurones|Catechols|Phenol ethers

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