| 释义 |
- References
- Further reading
{{Infobox_gene}}Leukocyte immunoglobulin-like receptor subfamily A member 4 is a protein that in humans is encoded by the LILRA4 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte immunoglobulin-like receptor gene cluster (LRC) at chromosomal region 19q13.4.[2]
}}References1. ^{{cite journal |vauthors=Wende H, Volz A, Ziegler A | title = Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster | journal = Immunogenetics | volume = 51 | issue = 8–9 | pages = 703–13 |date=Sep 2000 | pmid = 10941842 | pmc = | doi =10.1007/s002510000187 }}
2. ^1 {{cite web | title = Entrez Gene: LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23547| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Cho M, Ishida K, Chen J, etal |title=SAGE library screening reveals ILT7 as a specific plasmacytoid dendritic cell marker that regulates type I IFN production |journal=Int. Immunol. |volume=20 |issue= 1 |pages= 155–64 |year= 2008 |pmid= 18048391 |doi= 10.1093/intimm/dxm127 }}
- {{cite journal |vauthors=Sellick GS, Wade R, Richards S, etal |title=Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis |journal=Blood |volume=111 |issue= 3 |pages= 1625–33 |year= 2008 |pmid= 18006695 |doi= 10.1182/blood-2007-08-110130 }}
- {{cite journal |vauthors=Zhan X, Desiderio DM |title=Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry |journal=Anal. Biochem. |volume=354 |issue= 2 |pages= 279–89 |year= 2006 |pmid= 16777052 |doi= 10.1016/j.ab.2006.05.024 }}
- {{cite journal |vauthors=Cao W, Rosen DB, Ito T, etal |title=Plasmacytoid dendritic cell–specific receptor ILT7–FcɛRIγ inhibits Toll-like receptor–induced interferon production |journal=J. Exp. Med. |volume=203 |issue= 6 |pages= 1399–405 |year= 2006 |pmid= 16735691 |doi= 10.1084/jem.20052454 | pmc=2118323 }}
- {{cite journal |vauthors=Ju XS, Hacker C, Scherer B, etal |title=Immunoglobulin-like transcripts ILT2, ILT3 and ILT7 are expressed by human dendritic cells and down-regulated following activation |journal=Gene |volume=331 |issue= |pages= 159–64 |year= 2004 |pmid= 15094202 |doi= 10.1016/j.gene.2004.02.018 }}
- {{cite journal |vauthors=Tedla N, Bandeira-Melo C, Tassinari P, etal |title=Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 3 |pages= 1174–9 |year= 2003 |pmid= 12529506 |doi= 10.1073/pnas.0337567100 | pmc=298746 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Rissoan MC, Duhen T, Bridon JM, etal |title=Subtractive hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells |journal=Blood |volume=100 |issue= 9 |pages= 3295–303 |year= 2002 |pmid= 12384430 |doi= 10.1182/blood-2002-02-0638 }}
- {{cite journal |vauthors=Young NT, Canavez F, Uhrberg M, etal |title=Conserved organization of the ILT/LIR gene family within the polymorphic human leukocyte receptor complex |journal=Immunogenetics |volume=53 |issue= 4 |pages= 270–8 |year= 2001 |pmid= 11491530 |doi=10.1007/s002510100332 }}
{{refend}} 1 : Immunoglobulin superfamily |