| 词条 | Listeria monocytogenes non-coding RNA | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 |
| Name = Listeria snRNA rli22 | image = RF01457.png | width = 200 | caption = Predicted secondary structure of Listeria snRNA rli22 | Symbol = rli22 | AltSymbols = | Rfam = RF01457 | miRBase = | miRBase_family = | RNA_type = gene, snRNA | Tax_domain = Listeria | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }}Listeria monocytogenes is a gram positive bacterium and causes many food-borne infections such as Listeriosis. This bacteria is ubiquitous in the environment where it can act as either a saprophyte when free living within the environment or as a pathogen when entering a host organism. Many non-coding RNAs have been identified within the bacteria genome where several of these have been classified as novel non-coding RNAs and may contribute to pathogenesis.[1]Tiling arrays and mutagenesis identified many non-coding RNAs within the L. monocytogenes genome and the location of these non-coding RNAs within the bacterial genome was confirmed by RACE (rapid amplification of cDNA ends) analysis. These studies showed that the expression of many non-coding RNAs was dependent on the environment and that several of these non-coding RNAs act as cis-regulatory elements. Comparisons between previously characterized non-coding RNAs and those present in the L. monocyotogenes genome identified 50 novel non-coding RNAs in L. monocyotogenes. An additional comparative study between the pathogenic L. monocytogenes strain and the non pathogenic L. innocua strain identified several non-coding RNAs that are only present within L. monocytogenes which suggests that these ncRNAs may have a role in pathogenesis.[2] The tables below summarizes the location, flanking genes and also the characteristics of the novel small non-coding RNAs identified and the previously characterized non-coding RNAs present in L. monocytogenesNovel Non-coding RNAs
aArrows indicate the sense of the gene on the genome. Bold arrows indicate gene absent from L. innocua. Listeria monocytogenes EGD-e strain was used in these studies EMBL accession AL591824.1 Characterised non-coding RNAs
References1. ^{{cite journal |vauthors=Mandin P, Repoila F, Vergassola M, Geissmann T, Cossart P |title=Identification of new noncoding RNAs in Listeria monocytogenes and prediction of mRNA targets |journal=Nucleic Acids Res. |volume=35 |issue=3 |pages=962–74 |year=2007 |pmid=17259222 |pmc=1807966 |doi=10.1093/nar/gkl1096 |url=}} 2. ^{{cite journal |vauthors=Toledo-Arana A, Dussurget O, Nikitas G, etal |title=The Listeria transcriptional landscape from saprophytism to virulence |journal=Nature |volume=459 |issue=7249 |pages=950–6 |date=June 2009 |pmid=19448609 |doi=10.1038/nature08080 |url=}} 3. ^{{cite journal |vauthors=Burke TP, Loukitcheva A, Zemansky J, Wheeler R, Boneca IG, Portnoy DA |title=Listeria monocytogenes is resistant to lysozyme through the regulation, not the acquisition, of cell wall-modifying enzymes |journal=J. Bacteriol. |volume=196 |issue=21 |pages=3756–67 |year=2014 |pmid=25157076 |pmc=4248804 |doi=10.1128/JB.02053-14 |url=}} 4. ^{{cite journal |vauthors=Burke TP, Portnoy DA |title=SpoVG Is a Conserved RNA-Binding Protein That Regulates Listeria monocytogenes Lysozyme Resistance, Virulence, and Swarming Motility |journal=mBio |volume=7 |issue=2 |year=2016 |pmid=27048798 |pmc=4959528 |doi=10.1128/mBio.00240-16 |url=}} 5. ^{{cite journal |doi=10.1128/JB.00740-08 |vauthors=Nielsen JS, Olsen AS, Bonde M, Valentin-Hansen P, Kallipolitis BH |title=Identification of a sigma B-dependent small noncoding RNA in Listeria monocytogenes. |journal=J Bacteriol |volume=190 |issue=18 |pages=6264–70 |year=2008 |pmid=18621897 |pmc=2546787}} External links
| name = hidden | title = Gallery of secondary structure images | titlestyle = background:#e7dcc3 | state = autocollapse | list1 = {{Gallery | lines=4 | Image:RF01457.png|Listeria snRNA rli22: Predicted secondary structure taken from the Rfam database. Family RF01457. | Image:RF01458.png|Listeria snRNA rli23: Predicted secondary structure taken from the Rfam database. Family RF01458. | Image:RF01459.png|Listeria snRNA rliE: Predicted secondary structure taken from the Rfam database. Family RF01459. | Image:RF01460.png|Listeria snRNA rliH: Predicted secondary structure taken from the Rfam database. Family RF01460. | Image:RF01461.png|Listeria snRNA rli24: Predicted secondary structure taken from the Rfam database. Family RF01461. | Image:RF01462.png|Listeria snRNA rli26: Predicted secondary structure taken from the Rfam database. Family RF01462. | Image:RF01463.png|Listeria snRNA rli27: Predicted secondary structure taken from the Rfam database. Family RF01463. | Image:RF01464.png|Listeria snRNA rliA: Predicted secondary structure taken from the Rfam database. Family RF01464. | Image:RF01465.png|Listeria snRNA rli31: Predicted secondary structure taken from the Rfam database. Family RF01465. | Image:RF01466.png|Listeria snRNA rli34: Predicted secondary structure taken from the Rfam database. Family RF01466. | Image:RF01467.png|Listeria snRNA rli36: Predicted secondary structure taken from the Rfam database. Family RF01467. | Image:RF01468.png|Listeria snRNA rli32: Predicted secondary structure taken from the Rfam database. Family RF01468. | Image:RF01469.png|Listeria snRNA rli33: Predicted secondary structure taken from the Rfam database. Family RF01469. | Image:RF01470.png|Listeria snRNA rli38: Predicted secondary structure taken from the Rfam database. Family RF01470. | Image:RF01471.png|Listeria snRNA rliB: Predicted secondary structure taken from the Rfam database. Family RF01471. | Image:RF01472.png|Listeria snRNA rli40: Predicted secondary structure taken from the Rfam database. Family RF01472. | Image:RF01473.png|Listeria snRNA rli41: Predicted secondary structure taken from the Rfam database. Family RF01473. | Image:RF01474.png|Listeria snRNA rli42: Predicted secondary structure taken from the Rfam database. Family RF01474. | Image:RF01475.png|Listeria snRNA rli45: Predicted secondary structure taken from the Rfam database. Family RF01475. | Image:RF01476.png|Listeria snRNA rliF: Predicted secondary structure taken from the Rfam database. Family RF01476. | Image:RF01477.png|Listeria snRNA rli43: Predicted secondary structure taken from the Rfam database. Family RF01477. | Image:RF01478.png|Listeria snRNA rli47: Predicted secondary structure taken from the Rfam database. Family RF01478. | Image:RF01479.png|Listeria snRNA rli48: Predicted secondary structure taken from the Rfam database. Family RF01479. | Image:RF01480.png|Listeria snRNA rli52: Predicted secondary structure taken from the Rfam database. Family RF01480. | Image:RF01481.png|Listeria snRNA rli53: Predicted secondary structure taken from the Rfam database. Family RF01481. | Image:RF01482.png|Listeria snRNA rli55: Predicted secondary structure taken from the Rfam database. Family RF01482. | Image:RF01483.png|Listeria snRNA rli56: Predicted secondary structure taken from the Rfam database. Family RF01483. | Image:RF01484.png|Listeria snRNA rli59: Predicted secondary structure taken from the Rfam database. Family RF01484. | Image:RF01485.png|Listeria snRNA rli61: Predicted secondary structure taken from the Rfam database. Family RF01485. | Image:RF01486.png|Listeria snRNA rli62: Predicted secondary structure taken from the Rfam database. Family RF01486. | Image:RF01487.png|Listeria snRNA rliI: Predicted secondary structure taken from the Rfam database. Family RF01487. | Image:RF01488.png|Listeria snRNA rli49: Predicted secondary structure taken from the Rfam database. Family RF01488. | Image:RF01489.png|Listeria snRNA sbrA: Predicted secondary structure taken from the Rfam database. Family RF01489. | Image:RF01490.png|Listeria snRNA rli51: Predicted secondary structure taken from the Rfam database. Family RF01490. | Image:RF01491.png|Listeria snRNA rli54: Predicted secondary structure taken from the Rfam database. Family RF01491. | Image:RF01492.png|Listeria snRNA rli28: Predicted secondary structure taken from the Rfam database. Family RF01492. | Image:RF01493.png|Listeria snRNA rli37: Predicted secondary structure taken from the Rfam database. Family RF01493. | Image:RF01494.png|Listeria sRNA rliD: Predicted secondary structure taken from the Rfam database. Family RF01494. |}} }} 2 : Listeriaceae|Non-coding RNA |
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