| Name | Town/City | State | Notes | | Ann Arbor Hands-On Museum | Ann Arbor | Michigan |
| Above & Beyond Children's Museum | Sheboygan | Wisconsin |
| A.C. Gilbert's Discovery Village | Salem | Oregon | Named for Alfred Carlton Gilbert, inventor of the erector set |
| Adventure! Children's Museum | Eugene | Oregon | Founded in August 2015 |
| AHA! A Hands-on Adventure | Lancaster | Ohio |
| Amazement Square, The Rightmire Children's Museum | Lynchburg | Virginia |
| Arizona Museum for Youth | Mesa | Arizona | Only children's museum in U.S. that focuses on fine art; founded in 1980 |
| Bay Area Discovery Museum | Sausalito | California | Located on National Park land; founded in 1987 |
| Beaumont Children's Museum | Beaumont | Texas | Founded in 2008. Temporarily located at Beaumont Civic Center |
| Betty Brinn Children's Museum | Milwaukee | Wisconsin | Named for Milwaukee businesswoman Betty Brinn; Opened in 1995 |
| Boonshoft Museum of Discovery | Dayton | Ohio |
| Bootheel Youth Museum | Malden | Missouri |
| Boston Children's Museum | Boston | Massachusetts | Second oldest children's museum in the U.S.; recognized as LEED Gold certified by the U.S. Green Building Council; founded in 1913 |
| Bronzeville Children's Museum | Chicago | Illinois | Only African-American children's museum in the U.S. |
| Bronx Children's Museum | The Bronx | New York | Founded in 2005. |
| Brooklyn Children's Museum | Brooklyn | New York | First museum developed for children; founded in 1899 |
| Buell Children's Museum | Pueblo | Colorado | A program of the Sangre de Cristo Arts Center. |
| The Building for Kids, Inc. | Appleton | Wisconsin |
| Cape Cod Children's Museum | Mashpee | Massachusetts |
| Central Wisconsin Children's Museum | Stevens Point | Wisconsin | Opened in 1997. |
| Chesapeake Children's Museum | Annapolis | Maryland | Founded in 1994. |
| Chicago Children's Museum | Chicago | Illinois | Located on Navy Pier on Lake Michigan; founded in 1982 |
| Children's Discovery Museum | Normal | Illinois | Founded in 1988. |
| Children's Discovery Museum | Augusta | Maine |
| Children's Discovery Museum of the Desert | Rancho Mirage | California | Founded in 1986. |
| Children's Discovery Museum of San Jose | San Jose | California | Founded in 1990 |
| Children's Discovery Zone | Norfolk | Nebraska | Located within the Elkhorn Valley Museum and Research Center. |
| Children's Hands-On Museum | Tuscaloosa | Alabama | Opened in 1986. |
| Children's Maritime Museum at Port Jefferson | Port Jefferson | New York |
| Children's Museum of Acadiana | Lafayette | Louisiana | Opened in 1996. |
| Children's Museum of Atlanta | Atlanta | Georgia |
| Children's Museum of the Arts | Manhattan | New York |
| The Children's Museum of the Brazos Valley | Bryan | Texas |
| Children's Museum of Brownsville | Brownsville | Texas | Opened in 2005 |
| Children's Museum of Central Nebraska | Hastings | Nebraska | Opened in 2003 |
| The Children's Museum of Cleveland | Cleveland | Ohio |
| The Children's Museum of Denver | Denver | Colorado | Founded in 1973 |
| Children's Museum in Easton | North Easton | Massachusetts | Located in old fire station; founded in 1986 |
| Children's Museum of Eau Claire | Eau Claire | Wisconsin | Opened in 2004 |
| The Children's Museum in Edwardsville | Edwardsville | Illinois | Opened in 2003 |
| Children's Museum of Fond du Lac | Fond du Lac | Wisconsin | Opened in 2007 |
| Children's Museum of Hartford | West Hartford | Connecticut | Fifth oldest children's museum in the U.S.; founded in 1927 |
| Children's Museum of the Highlands | Sebring | Florida | Opened in 1990 |
| Children's Museum at Holyoke | Holyoke | Massachusetts | Founded in 1984 by the Junior League of Holyoke,[1] moved to current location in 1992.[2][3] |
| Children's Museum of Houston | Houston | Texas | Founded in 1980; opened new addition in 2009 |
| Children's Museum of Illinois | Decatur | Illinois |
| The Children's Museum of Indianapolis | Indianapolis | Indiana | Largest children's museum in the world; founded in 1924 |
| Children's Museum of La Crosse | La Crosse | Wisconsin |
| Children's Museum at La Habra | La Habra | California | Located in an historic train depot; opened in 1977 |
| Children's Museum of the Lowcountry | Charleston | South Carolina |
| Children's Museum of Maine | Portland | Maine | Founded in 1976 |
| Children's Museum of Manhattan | New York City | New York |
| Children's Museum of Memphis | Memphis | Tennessee | Located in former National Guard Armory; opened in 1990 |
| Children's Museum, Missoula | Missoula | Montana |
| Children's Museum of Montana | Great Falls | Montana |
| The Children's Museum of New Hampshire | Dover | New Hampshire |
| The Children's Museum of Northeast Montana | Glasgow | Montana | Opened in 2006 |
| The Children's Museum of Northern Nevada | Carson City | Nevada |
| The Children's Museum in Oak Lawn | Oak Lawn | Illinois |
| Children's Museum of Oak Ridge | Oak Ridge | Tennessee | Opened in 1973 |
| Children's Museum of the Ohio Valley | Wheeling | West Virginia |
| Children's Museum at the Paso Robles Volunteer Firehouse | Paso Robles | California | Founded in 2002; |
| Children's Museum of Phoenix | Phoenix | Arizona | Founded in 1998; |
| Children's Museum of Pittsburgh | Pittsburgh | Pennsylvania |
| Children's Museum of Richmond | Richmond | Virginia | Opened in 1981 |
| The Children's Museum of Rose Hill Manor Park | Frederick | Maryland |
| The Children's Museum at Saratoga | Saratoga Springs | New York |
| The Children's Museum of Science and Technology | Troy | New York | Founded in 1954 by the Junior League, formerly the Junior Museum |
| The Children's Museum, Seattle | Seattle | Washington | Founded in 1979 |
| Children's Museum of the Sierra | Oakhurst | California |
| Children's Museum of Skagit County | Burlington | Washington | Located in Cascade Mall |
| The Children's Museum of Sonoma County | Santa Rosa | California |
| The Children's Museum of South Carolina | Myrtle Beach | South Carolina |
| Children's Museum of Southeastern Connecticut | Niantic | Connecticut | Created in 1992 |
| Children's Museum of Stockton | Stockton | California |
| Children's Museum of Tacoma | Tacoma | Washington | Opened in 1986 |
| Children's Museum of the Treasure Coast | Stuart | Florida | Located in a former chapel and auditorium building in Indian Riverside Park in Jensen Beach; opened in 2008. |
| Children's Museum Tucson | Tucson | Arizona |
| The Children's Museum of the Upstate | Greenville | South Carolina |
| Children's Museum of the Valley | Youngstown | Ohio | Opened in 2004 |
| Children's Museum of Virginia | Portsmouth | Virginia |
| Children's Museum of Walla Walla | Walla Walla | Washington |
| The Children's Museum of Wilmington | Wilmington | North Carolina |
| Children's Museum of Winston-Salem | Winston-Salem | North Carolina |
| The Children's Museum at Yunker Farm | Fargo | North Dakota | Located in first brick house in the Dakota territory |
| Children's Neighborhood Museum | Round Lake | Illinois | Part of the Round Lake Area Park District |
| The Children's Playhouse | Boone | North Carolina |
| Children's Science Explorium | Boca Raton | Florida |
| Community Children's Museum | Dover | New Jersey |
| Connecticut Children's Museum | New Haven | Connecticut |
| Cookeville Children's Museum | Cookeville | Tennessee | Opened in 2007 |
| Creative Discovery Museum | Chattanooga | Tennessee | Opened in 1995 |
| Curious Kids' Museum | St. Joseph | Michigan | Located in Veterans Memorial Hall in St. Joseph; founded in 1989 |
| Delaware Children's Museum | Wilmington | Delaware | Located on Wilmington Riverfront |
| Discovery Center at Murfree Spring | Murfreesboro | Tennessee |
| The Discovery Center of the Southern Tier | Binghamton | New York |
| Discovery Center Museum | Rockford | Illinois |
| Discovery Creek Children's Museum | Washington | District of Columbia |
| Discovery Depot Children's Museum | Galesburg | Illinois |
| Discovery Gateway | Salt Lake City | Utah | Formerly known as the Children's Museum of Utah |
| Discovery Museum | Eureka | California |
| The Discovery Playhouse | Cape Girardeau | Missouri |
| Discovery Science Place | Tyler | Texas |
| Don Harrington Discovery Center | Amarillo | Texas |
| Duke Energy Children's Museum | Cincinnati | Ohio |
| Duluth Children's Museum | Duluth | Minnesota |
| DuPage Children's Museum | Naperville | Illinois |
| Earlyworks | Huntsville | Alabama |
| East Tennessee Discovery Center | Knoxville | Tennessee |
| EdVenture Children's Museum | Columbia | South Carolina | Opened in 2003 |
| Escondido Children's Museum | Escondido | California |
| expERIEnce Children's Museum | Erie | Pennsylvania |
| ¡Explora! | Albuquerque | New Mexico |
| Exploration Station | Bourbonnais | Illinois |
| Exploration Station | Lumberton | North Carolina |
| Explorations V Children's Museum | Lakeland | Florida |
| Explore & More Children's Museum | East Aurora | New York |
| Explorium of Lexington | Lexington | Kentucky |
| Family Museum | Bettendorf | Iowa |
| Fascinate-U Children's Museum | Fayetteville | North Carolina |
| Fingerprints Youth Museum | Hemet | California |
| Flint Children's Museum | Flint | Michigan |
| Forever Curious Children's Museum | Fennville | Michigan |
| Fort Worth Museum of Science and Industry | Fort Worth | Texas | First children's museum in Texas; founded in 1941 |
| Garden State Discovery Museum | Cherry Hill | New Jersey |
| Gaylord Discovery Center | Gaylord | Michigan | Opened in 2010. Theme: Mechanics |
| Georgia Children's Museum | Macon | Georgia |
| Glazer Children's Museum | Tampa | Florida | Opened in 2010. Named after the Glazer Family of the Tampa Bay Area.[4] |
| Grand Rapids Children's Museum | Grand Rapids | Michigan |
| Great Explorations Children's Museum | St. Petersburg | Florida |
| Great Lakes Children's Museum | Traverse City | Michigan |
| Greensboro Children's Museum | Greensboro | North Carolina |
| Gull Wings Children's Museum | Oxnard | California |
| Habitot Children's Museum | Berkeley | California |
| Hands On! A Child's Gallery | Hendersonville | North Carolina |
| Hands On Children's Museum | Olympia | Washington |
| Hands-on House Children's Museum | Lancaster | Pennsylvania |
| Hannah Lindahl Children's Museum | Mishawaka | Indiana |
| Harrisonburg Children's Museum | Harrisonburg | Virginia | Opened in 2003 |
| Hawaii Children's Discovery Center | Honolulu | Hawaii |
| Healthworks! Kids' Museum | South Bend | Indiana |
| Imaginarium of South Texas | Laredo | Texas | Opened in 1991 |
| Imagination Place | Gadsden | Alabama |
| The Imagination Workshop, Temecula's Children's Museum | Temecula | California |
| Imagine Children's Museum | Everett | Washington |
| Imagine Nation Children's Museum | Bristol | Connecticut |
| ImagineU Children's Museum | Visalia | California |
| The Joe & Joan Martin Center | Charlotte | North Carolina | Opened in 2005 |
| Impression 5 Science Center | Lansing | Michigan |
| Interactive Neighborhood for Kids | Gainesville | Georgia |
| The Iowa Children's Museum | Coralville | Iowa |
| Jasmine Moran Children's Museum | Seminole | Oklahoma |
| Jeanes Discovery Center | Waco | Texas | Located within Baylor University's Mayborn Museum Complex; |
| The Jersey Explorer Children's Museum | East Orange | New Jersey |
| Kaleidoscope (Kansas City, Missouri) | Kansas City | Missouri |
| Kearney Area Children's Museum | Kearney | Nebraska |
| Kern County Museum | Bakersfield | California |
| Kidcity Children's Museum | Middletown | Connecticut |
| Kidscommons | Columbus | Indiana |
| Kidsenses, Inc. | Rutherfordton | North Carolina |
| Kidsfirst Children's Museum | South Bend | Indiana |
| Kids 'N' Stuff | Albion | Michigan |
| Kidspace Children's Museum | Pasadena | California |
| KidsQuest Children's Museum | Bellevue | Washington |
| Kid Time! Discovery Experience | Medford | Oregon |
| The Kidzeum | Grenada | Mississippi |
| Kidzone Museum | Truckee | California |
| Kidzu Children's Museum | Chapel Hill | North Carolina | Founded in March 2006 |
| Koch Family Children's Museum of Evansville | Evansville | Indiana |
| Kohl Children's Museum | Glenview | Illinois |
| Liberty Science Center | Jersey City | New Jersey |
| Lied Discovery Children's Museum | Las Vegas | Nevada |
| Lincoln Children's Museum | Lincoln | Nebraska | First green building in Lincoln |
| Long Island Children's Museum | Garden City | New York |
| Louisiana Children's Museum | New Orleans | Louisiana |
| Lutz Children's Museum | Manchester | Connecticut |
| Lynn Meadows Discovery Center | Gulfport | Mississippi |
| Madison Children's Museum | Madison | Wisconsin | Opened in 1991 |
| The Magic House, St. Louis Children's Museum | St. Louis | Missouri | Opened in 1979 |
| Maine Discovery Museum | Bangor | Maine |
| Marbles Kids Museum | Raleigh | North Carolina |
| McKenna Children's Museum | New Braunfels | Texas |
| Miami Children's Museum | Miami | Florida |
| Mid-Hudson Children's Museum | Poughkeepsie | New York |
| Mid-Michigan Children's Museum | Saginaw | Michigan |
| Minnesota Children's Museum | St. Paul | Minnesota |
| Mississippi Children's Museum | Jackson | Mississippi |
| Mobius Kids | Spokane | Washington | Part of Mobius Spokane |
| Monterey Youth Museum | Monterey | California |
| The Most (Museum Of Science & Technology) | Syracuse | New York |
| Mountain Top Children's Museum | Breckenridge | Colorado |
| MOXI, The Wolf Museum of Exploration + Innovation | Santa Barbara | California | Opened on February 25, 2017 |
| My Jewish Discovery Place | Fort Lauderdale | Florida |
| National Museum of Play | Rochester | New York | Second largest children’s museum in the country |
| The New Children's Museum | San Diego | California |
| Northeast Texas Children's Museum | Commerce | Texas | Located within Texas A&M University-Commerce; opened in 2002 |
| North Platte Area Children's Museum | North Platte | Nebraska |
| Northwoods Children's Museum | Eagle River | Wisconsin |
| Omaha Children's Museum | Omaha | Nebraska | Founded in 1976 |
| Orpheum Children's Science Museum | Champaign | Illinois |
| Our World, Children's Global Discovery Museum | Cohasset | Massachusetts |
| Pennypickle's Workshop | Temecula | California |
| Phelps Youth Pavilion | Waterloo | Iowa |
| Please Touch Museum | Philadelphia | Pennsylvania | Located within Memorial Hall, which was built for the 1876 Centennial Exposition |
| Port Discovery | Baltimore | Maryland |
| Portland Children's Museum | Portland | Oregon | Sixth oldest children's museum in the United States |
| Pretend City Children's Museum | Irvine | California |
| Providence Children's Museum | Providence | Rhode Island | Rhode Island's first and only children's museum |
| Raven Hill Discovery Center | Boyne City | Michigan | Established in 1991 |
| Sacramento Children's Museum | Sacramento | California | Opened in 2011 |
| San Antonio Children's Museum | San Antonio | Texas | Opened in 1995 |
| The Sandbox | Hilton Head Island | South Carolina |
| Sandcastles Children's Museum | Ludington | Michigan | Opened in 2007; operates during the summer only |
| San Luis Obispo Children's Museum | San Luis Obispo | California |
| Santa Fe Children's Museum | Santa Fe | New Mexico |
| Schoolhouse Children's Museum and Learning Center | Boynton Beach | Florida |
| Science and Discovery Center of Northwest Florida | Panama City | Florida |
| Science City at Union Station | Kansas City | Missouri | Founded in 1999 |
| Seminole County School Student Museum | Sanford | Florida |
| Shenandoah Valley Discovery Museum | Winchester | Virginia |
| St. George Children's Museum | St.George | Utah | Opened in 2013 |
| Staten Island Children's Museum | Staten Island | New York |
| Stepping Stones Museum for Children | Norwalk | Connecticut |
| Texoma Children's Museum | Denison | Texas |
| The Thinkery | Austin | Texas | Opened in 1987; formerly Austin Children's Museum; opening December 2013 |
| T.R.E.E. House Children's Museum | Alexandria | Louisiana |
| Treehouse Children's Museum | Ogden | Utah | Opened in 1992 |
| Upper Peninsula Children's Museum | Marquette | Michigan |
| Utica Children's Museum | Utica | New York | Founded in October 1963 by the Junior League, formerly The Children's Museum of History, Natural History & Science |
| Virginia Discovery Museum | Charlottesville | Virginia |
| WonderLab Museum of Science, Health & Technology | Bloomington | Indiana |
| Wonderfeet Kids Museum | Rutland | Vermont |
| Wonderscope Children's Museum of Kansas City | Shawnee | Kansas |
| Wonder Works | Oak Park | Illinois |
| The Woodlands Children's Museum | The Woodlands | Texas |
| Working Wonders Children's Museum | Bend | Oregon |
| World Awareness Children's Museum | Glen Falls, New York | New York | Created in 1995 |
| WOW! Children's Museum | Lafayette | Colorado |
| Young at Art Museum | Davie | Florida |
| Zimmer Children's Museum | Los Angeles | California |
|
1. ^{{cite news|last=Matsuo|first=Reiko|title=Holyoke museum exhibits emphasize animals for kids|date=November 9, 1984|page=50|work=Springfield Union|location=Springfield, Mass.}}
2. ^[Query- "Children's Museum at Holyoke, Inc."], Massachusetts Corp. Card Search, Corporation Cards of the Commonwealth of Massachusetts, Secretary of the Commonwealth
3. ^Parcel 085-00-051, Holyoke Assessor's Database
4. ^{{Cite news|url=http://www.buccaneers.com/glazerfamilyfoundation/gcm.html|title=Tampa Bay Buccaneers {{!}} Glazer Children's Museum|access-date=2017-01-18}}
{{DEFAULTSORT:List Of Children's Museums In The United States}}