The show broadcasts Sundays through Thursdays, with no show on Friday or Saturday. Since it broadcasts at 10 p.m. to 12 a.m PT occasionally shows will be listed incorrectly with the next day's date. If a show's date corresponds to a Friday or a Saturday, it is almost certainly incorrect. Sunday episodes are identified in the table by gray shading.
| Date | Guest(s) | Notes |
|---|
| 1997-01-05 |
| 1997-01-12 |
| 1997-01-16 | Shannen Doherty, Jennifer Blanc & Jason London | From the movie Friends 'Til the End |
| 1997-01-19 | Jeremy McGrath |
| 1997-01-26 |
| 1997-01-28 | Cake |
| 1997-02-02 |
| 1997-02-09 |
| 1997-02-16 |
| 1997-02-23 |
| 1997-03-02 |
| 1997-03-09 |
| 1997-03-11 | The Verve Pipe | Band performs an a cappella rendition of Cheap Trick song "Surrender" |
| 1997-03-16 |
| 1997-03-23 |
| 1997-03-27 | Jennifer Grey |
| 1997-03-30 |
| 1997-04-06 |
| 1997-04-13 |
| 1997-04-20 |
| 1997-04-27 |
| 1997-05-04 |
| 1997-05-11 |
| 1997-05-15 | Clive Barker |
| 1997-05-18 | Nicholas Brendon | From Buffy the Vampire Slayer |
| 1997-05-20 | Sneaker Pimps |
| 1997-05-21 | Margaret Cho |
| 1997-05-22 | No guest |
| 1997-05-25 |
| 1997-05-26 | No guest - Natalia Cigliuti was scheduled, didn't come |
| 1997-05-27 | Stephen Baldwin |
| 1997-05-28 | Tyra Banks |
| 1997-05-29 | David Spade | Tom Arnold was scheduled, then postponed |
| 1997-06-01 |
| 1997-06-02 | No guest |
| 1997-06-03 | Kennedy |
| 1997-06-04 | Sugar Ray |
| 1997-06-05 | Michael Penn |
| 1997-06-08 |
| 1997-06-10 | No guest? |
| 1997-06-10 | The Offspring |
| 1997-06-11 | The Offspring |
| 1997-06-12 | No guest, pie in the face story |
| 1997-06-12 | Tom Arnold |
| 1997-06-15 | Don Ho |
| 1997-06-16 | Drew's niece Bonnie |
| 1997-06-17 | Margaret Cho |
| 1997-06-18 | Toad the Wet Sprocket |
| 1997-06-19 | Tom Arnold |
| 1997-06-22 |
| 1997-06-29 |
| 1997-07-06 |
| 1997-07-09 | Suzanne Vega |
| 1997-07-10 | Kim Coles |
| 1997-07-13 |
| 1997-07-14 | that dog. |
| 1997-07-15 | No guest - Nora Dunn was scheduled but canceled. |
| 1997-07-16 | K's Choice |
| 1997-07-20 |
| 1997-07-21 | Bobcat Goldthwait |
| 1997-07-22 | John Leguizamo and Michael Jai White |
| 1997-07-23 | Lamont Bentley |
| 1997-07-27 |
| 1997-07-30 | Ric Ocasek | From the band The Cars; hosted by Dr. Marcel & Adam Carolla |
| 1997-08-03 |
| 1997-08-10 | Electric toothbrush story |
| 1997-08-13 | Paulina Pinsky | Dr. Drew's daughter |
| 1997-08-14 | Dwight Yoakam |
| 1997-08-17 |
| 1997-08-20 | Orbit |
| 1997-08-24 |
| 1997-08-25 |
| 1997-08-26 | John Popper | From the band Blues Traveler |
| 1997-08-31 |
| 1997-09-01 | Paul Draper & Dominic Chad | From the band Mansun; hosted by Dr. Drew & Brad Wright from KROQ-FM |
| 1997-09-07 | blink-182 |
| 1997-09-08 | Duncan Sheik |
| 1997-09-09 | Blink-182 |
| 1997-09-09 | Sinjin Smith & Dain Blanton | Pro beach volleyball players |
| 1997-09-10 | Smash Mouth |
| 1997-09-14 |
| 1997-09-15 | Sugar Ray |
| 1997-09-16 | Insane Clown Posse |
| 1997-09-18 | Fiona Apple |
| 1997-09-21 |
| 1997-09-22 | Jon Pebsworth & Jonas Kleiner | From the band Buck-O-Nine |
| 1997-09-23 | Our Lady Peace |
| 1997-09-24 | Ruth-Ann Boyle & Tim Kellett | From the band Olive |
| 1997-09-28 | Paid not to masturbate |
| 1997-09-30 | Jessica Bowman | From the TV show Dr. Quinn, Medicine Woman |
| 1997-10-01 | Ken Marino | From the TV show Men Behaving Badly |
| 1997-10-02 | Art Alexakis, Craig Montoya & Greg Eklund | From the band Everclear |
| 1997-10-05 |
| 1997-10-09 | Duran Duran |
| 1997-10-12 | Goldfinger |
| 1997-10-13 | Jenica Bergere & Dina Spybey | From the TV show Men Behaving Badly |
| 1997-10-19 | No guest, pie time |
| 1997-10-20 | Rick James |
| 1997-10-21 | The Aquabats |
| 1997-10-22 | Charles Fleischer |
| 1997-10-23 | Tom Silver & Sunny Garcia |
| 1997-10-26 | Sugar Ray |
| 1997-10-28 | David Faustino |
| 1997-10-29 | No guest |
| 1997-11-02 | Hosted by Dr. Bruce & Adam Carolla, no guest |
| 1997-11-03 | Chumbawamba | Promoting the album Tubthumper |
| 1997-11-04 | Kennedy |
| 1997-11-06 | The Specials |
| 1997-11-09 | Leah Remini | Hosted by Dr. Bruce & Adam Carolla |
| 1997-11-10 | David Spade & Wendie Malick |
| 1997-11-11 | Joey Ramone |
| 1997-11-16 | Gedde Watanabe |
| 1997-11-19 | Catherine Bell | From the TV show JAG |
| 1997-11-23 |
| 1997-11-30 | Hosted by Dr. Bruce & Adam Carolla |
| 1997-12-03 | Gavin Rossdale |
| 1997-12-04 | Björk |
| 1997-12-07 | No guest, "Sky High" |
| 1997-12-08 | David Arquette | From the movie Scream 2 |
| 1997-12-09 | Portia de Rossi |
| 1997-12-09 | Jamie Kennedy | From the movie Scream 2 |
| 1997-12-11 | John Hiatt |
| 1997-12-14 | No guest |
| 1997-12-15 | Lords of Acid |
| 1997-12-16 | Buster Poindexter |
| 1997-12-21 |
| 1997-12-22 | Elise Neal |
| 1997-12-28 |