| Name | Entered office | Left office | | Dr. Juan Ramón Chávez | 1968 | 1988 |
| Dr. Ezequiel González Alsina | 1988 | 1989 |
| Dr. Alberto Nogués | 1989 | 1990 |
| Dr. Delio Fariña | 1990 | 1991 |
| Dr. Waldino Ramón Lovera | 1990 | 1991 |
| Dr. Gustavo Díaz de Vivar | 1991 | 1992 |
| Dr. Gustavo Díaz de Vivar | 1992 | 1993 |
| Dr. Evelio Fernández Arévalos | 1993 | 1994 |
| Dr. Evelio Fernández Arévalos | 1994 | 1995 |
| Esc. Milciades Rafael Casabianca | 1995 | 1996 |
| Dr. Miguel Abdón Saguier | 1996 | 1997 |
| Dr. Rodrigo Campos Servera | 1997 | 1998 |
| Dr. Luis Ángel González Macchi | 1998 | 1999 |
| Don Juan Carlos Galaverna Delvalle | 1999 | 2000 |
| Prof. dr. Juan Roque Galeano Vilalba | 2000 | 2001 |
| Prof. dr. Juan Roque Galeano Vilalba | 2001 | 2002 |
| Don Juan Carlos Galaverna Delvalle | 2002 | 2003 |
| Dr. Carlos Mateo Balmelli | 2003 | 2004 |
| Dr. Miguel Carrizosa | 2004 | 2005 |
| Dr. Carlos Filizzola | 2005 | 2006 |
| Enrique González Quintana | 2006 | 2007 |
| Miguel Abdón SAguier Carmona | 2007 | 2008 |
| Enrique González Quintana | 2008 | 2009 |
| Miguel Garrizosa Galiano | 2009 | 2010 |
| Óscar Alberto González Daher | 2010 | 2011 |
| Jorge Antonio Oviedo Matto | 2011 | 2012 |
| Alfredo Luis Jaeggli Caballero | 2012 | 2013 |
| Julio César Velázquez Tillería | 2013 | 2014 |
| Blas Antonio Llano Ramos | 2014 | 2015 |
| Mario Abdo Benítez | 2015 | 2016 |
| Roberto Ramón Acevedo Quevedo | 2016 | 2017 |
| Fernando Armindo Lugo Méndez | 2017 | 2018 |
| Silvio Adalberto Ovelar Benítez | 2018 | Present |
1. ^{{cite web |url=http://www.senado.gov.py/index.php/senado/autoridades/expresidentes|publisher=The Senate of Paraguay's website|title=Expresidentes|date=28 January 2019}}