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词条 Long range pseudoknots
释义

  1. References

  2. External links

{{Infobox rfam
| Name = Long range pseudoknot
| image = RF01086.png
| width = 200
| caption = Secondary structure of the long range pseudoknot
| Symbol =
| AltSymbols =
| Rfam = RF01086
| miRBase =
| miRBase_family =
| RNA_type = Cis-reg
| Tax_domain = Eukaryote Prokaryote
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| PDB =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}

A long range pseudoknot is a pseudoknot containing a long loop region, and may be a mechanism of translational control.

A long range pseudoknot is thought to negatively regulate the translation of the IF3-L35-L20 operon in E. coli. This operon encodes the translation initiation factor IF-3 and ribosomal proteins L35 and L20. In this example, the RNA-RNA interaction occurs between nucleotides separated by a 300 nucleotide loop region.[1]

A long range pseudoknot is also believed to be required for the activity of the Neurospora VS ribozyme.[2]

References

1. ^{{cite journal | title = A long-range RNA-RNA interaction forms a pseudoknot required for translational control of the IF3-L35-L20 ribosomal protein operon in Escherichia coli | journal = EMBO J | year = 1996| first = C | last = Chiaruttini |author2=M Milet |author3=M Springer | volume = 15| issue = 16 | pages = 4402–13| pmid = 8861967 | pmc = 452164}}
2. ^{{cite journal | title = A long-range pseudoknot is required for activity of the Neurospora VS ribozyme | journal = EMBO J | year = 1996| first = T | last = Rastogi |author2=T L Beattie |author3=J E Olive |author4=R A Collins | volume = 15| issue = 11 | pages = 2820–25| pmid = 8654379| pmc=450219}}

External links

  • Rfam entry for Long range pseudoknots{{dead link|date=January 2018 |bot=InternetArchiveBot |fix-attempted=yes }}

1 : Non-coding RNA

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