词条 | Long range pseudoknots |
释义 |
| Name = Long range pseudoknot | image = RF01086.png | width = 200 | caption = Secondary structure of the long range pseudoknot | Symbol = | AltSymbols = | Rfam = RF01086 | miRBase = | miRBase_family = | RNA_type = Cis-reg | Tax_domain = Eukaryote Prokaryote | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} A long range pseudoknot is a pseudoknot containing a long loop region, and may be a mechanism of translational control. A long range pseudoknot is thought to negatively regulate the translation of the IF3-L35-L20 operon in E. coli. This operon encodes the translation initiation factor IF-3 and ribosomal proteins L35 and L20. In this example, the RNA-RNA interaction occurs between nucleotides separated by a 300 nucleotide loop region.[1] A long range pseudoknot is also believed to be required for the activity of the Neurospora VS ribozyme.[2] References1. ^{{cite journal | title = A long-range RNA-RNA interaction forms a pseudoknot required for translational control of the IF3-L35-L20 ribosomal protein operon in Escherichia coli | journal = EMBO J | year = 1996| first = C | last = Chiaruttini |author2=M Milet |author3=M Springer | volume = 15| issue = 16 | pages = 4402–13| pmid = 8861967 | pmc = 452164}} 2. ^{{cite journal | title = A long-range pseudoknot is required for activity of the Neurospora VS ribozyme | journal = EMBO J | year = 1996| first = T | last = Rastogi |author2=T L Beattie |author3=J E Olive |author4=R A Collins | volume = 15| issue = 11 | pages = 2820–25| pmid = 8654379| pmc=450219}} External links
1 : Non-coding RNA |
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