| 词条 | LPK-26 |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 451562149 | IUPAC_name = 2-(3,4-dichlorophenyl)-N-[(2S)-1-(2,5-dihydropyrrol-1-yl)-3-methylbutan-2-yl]-N-methylacetamide | image = LPK-26_structure.png | width = 200 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 492451-07-7 | ATC_prefix = | ATC_suffix = | PubChem = 10043746 | IUPHAR_ligand = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 8219310 | C=18 | H=24 | Cl=2 | N=2 | O=1 | molecular_weight = 355.301 g/mol | smiles = CC(C)[C@@H](CN1CC=CC1)N(C)C(=O)CC2=CC(=C(C=C2)Cl)Cl | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C18H24Cl2N2O/c1-13(2)17(12-22-8-4-5-9-22)21(3)18(23)11-14-6-7-15(19)16(20)10-14/h4-7,10,13,17H,8-9,11-12H2,1-3H3/t17-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = QFAIAMMFKKYCTL-QGZVFWFLSA-N }}LPK-26 is a potent and selective κ-opioid agonist, and has analgesic effects.[1] References1. ^{{cite journal |vauthors=Tao YM, Li QL, Zhang CF, Xu XJ, Chen J, Ju YW, Chi ZQ, Long YQ, Liu JG |title=LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential |journal=European Journal of Pharmacology |volume=584 |issue=2-3 |pages=306–11 |date=April 2008 |pmid=18353307 |doi=10.1016/j.ejphar.2008.02.028 |url=}} {{Opioidergics}}{{analgesic-stub}} 5 : Acetamides|Kappa agonists|Chloroarenes|Pyrrolidines|Synthetic opioids |
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