| 释义 |
- References
- Further reading
{{Infobox_gene}}Leucine-rich repeat serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the LRRK1 gene.[1][2][3]{{PBB_Summary
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}}References1. ^{{cite journal |vauthors=Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 8 | issue = 2 | pages = 85–95 |date=May 2001 | pmid = 11347906 | pmc = | doi =10.1093/dnares/8.2.85 }}
2. ^{{cite journal |vauthors=Bosgraaf L, Van Haastert PJ | title = Roc, a Ras/GTPase domain in complex proteins | journal = Biochim Biophys Acta | volume = 1643 | issue = 1-3 | pages = 5–10 |date=Dec 2003 | pmid = 14654223 | pmc = | doi =10.1016/j.bbamcr.2003.08.008 }}
3. ^{{cite web | title = Entrez Gene: LRRK1 leucine-rich repeat kinase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79705| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
- {{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Korr D, Toschi L, Donner P, etal |title=LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain. |journal=Cell. Signal. |volume=18 |issue= 6 |pages= 910–20 |year= 2006 |pmid= 16243488 |doi= 10.1016/j.cellsig.2005.08.015 }}
- {{cite journal |vauthors=Zody MC, Garber M, Sharpe T, etal |title=Analysis of the DNA sequence and duplication history of human chromosome 15. |journal=Nature |volume=440 |issue= 7084 |pages= 671–5 |year= 2006 |pmid= 16572171 |doi= 10.1038/nature04601 }}
- {{cite journal |vauthors=Haugarvoll K, Toft M, Ross OA, etal |title=Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway. |journal=Neurosci. Lett. |volume=416 |issue= 3 |pages= 299–301 |year= 2007 |pmid= 17324517 |doi= 10.1016/j.neulet.2007.02.020 }}
- {{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
- {{cite journal |vauthors=Greggio E, Lewis PA, van der Brug MP, etal |title=Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1. |journal=J. Neurochem. |volume=102 |issue= 1 |pages= 93–102 |year= 2007 |pmid= 17394548 |doi= 10.1111/j.1471-4159.2007.04523.x }}
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