| 词条 | Lurosetron |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449870959 | IUPAC_name = 6-fluoro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one | image = Lurosetron.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 128486-54-4 | CAS_supplemental = {{CAS|143486-90-2}} (mesylate) | ATC_prefix = none | ATC_suffix = | ATC_supplemental = | PubChem = 172999 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = G694G740ZP | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D04821 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 151068 | chemical_formula = | C=17 | H=17 | F=1 | N=4 | O=1 | molecular_weight = 312.341 g/mol | smiles = CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=C(N3C)C(=CC=C4)F | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C17H17FN4O/c1-10-13(20-9-19-10)8-22-7-6-14-15(17(22)23)11-4-3-5-12(18)16(11)21(14)2/h3-5,9H,6-8H2,1-2H3,(H,19,20) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = NUMKWGDDRWJQMY-UHFFFAOYSA-N }}Lurosetron (INN) is a serotonin 5-HT3 receptor antagonist.[1] SynthesisReferences1. ^Prakash SP, Cable KM, Correa ID, Fellows L, Montgomery S, Newman JJ, Waterhouse L, Wells GN, Sutherland DR. Synthesis of isotopically labelled pyridoindolone 5-HT3 receptor antagonists. Journal of Labelled Compounds and Radiopharmaceuticals. 1995; 36(10):993-1007. {{gastrointestinal-drug-stub}} 2 : 5-HT3 antagonists|Imidazoles |
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