| 词条 | Lymphocryptovirus | ||||||||||||||||||||||||||||
| 释义 |
| image = Epstein Barr Virus virions EM 10.1371 journal.pbio.0030430.g001-L.JPG | image_alt = Electron microscopic image of two "Human gammaherpesvirus 4" virions (viral particles) showing round capsids (protein-encased genetic material) loosely surrounded by the membrane envelope | image_caption = Electron micrograph of two Human gammaherpesvirus 4 virions (viral particles) showing round capsids loosely surrounded by the membrane envelope | taxon = Lymphocryptovirus | authority = | synonyms = Unnamed genus 3 | synonyms_ref = [1] | type_species = Human gammaherpesvirus 4 | subdivision_ranks = Species | subdivision =
}}Lymphocryptovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. This genus includes the human-infecting Human gammaherpesvirus 4 (Epstein–Barr virus), as well as viruses that infect both Old World monkeys and New World monkeys.[2] Other names for the Lymphocryptovirus genus include Lymphocryptoviridae and gamma-1 herpesviruses. There are currently eight species in this genus including the type species Human gammaherpesvirus 4. Diseases associated with this genus include: mononucleosis, Burkitt's lymphoma, and nasopharyngeal carcinoma.[3][4] TaxonomyGroup: dsDNAOrder: HerpesviralesFamily: Herpesviridae Subfamily: Gammaherpesvirinae Genus: Lymphocryptovirus
Alternate Names
StructureViruses in Lymphocryptovirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 180kb in length.[3]
Life cycleViral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Human and mammals serve as the natural host. Transmission routes are zoonosis, bite, contact, and saliva.[3]
References1. ^{{cite web |title=ICTV Taxonomy history: Lymphocryptovirus |url=https://talk.ictvonline.org/taxonomy/p/taxonomy-history?taxnode_id=20181482 |website=International Committee on Taxonomy of Viruses (ICTV) |accessdate=10 January 2019 |language=en |format=html}} 2. ^{{cite journal |vauthors=Wang F, Rivailler P, Rao P, Cho Y |title=Simian homologues of Epstein-Barr virus|journal=Philos Trans R Soc Lond B Biol Sci |volume= 356|pmid= 11313007 |doi=10.1098/rstb.2000.0776 |year=2001 |issue=1408 |pages=489–97 |pmc=1088440}} 3. ^1 2 {{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/185.html|publisher=ExPASy|accessdate=15 June 2015}} 4. ^1 {{cite web|last1=ICTV|title=Virus Taxonomy: 2014 Release|url=http://ictvonline.org/virusTaxonomy.asp|accessdate=15 June 2015}} External links
1 : Gammaherpesvirinae |
||||||||||||||||||||||||||||
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。