| 词条 | Mabuterol |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 462095773 | ImageFile=Mabuterol.svg | ImageSize=250 | IUPACName=(RS)-1-[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol | OtherNames= | Section1 = {{Chembox Identifiers | UNII_Ref = {{fdacite|correct|FDA}} | UNII = R4K19W6S7Q | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 3857 | InChI = 1/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3 | InChIKey = JSJCTEKTBOKRST-UHFFFAOYAW | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 86749 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = JSJCTEKTBOKRST-UHFFFAOYSA-N | CASNo_Ref = {{cascite|changed|??}} | CASNo = 56341-08-3 | PubChem = 3995 | SMILES = Clc1cc(cc(c1N)C(F)(F)F)C(O)CNC(C)(C)C | MeSHName = mabuterol | Section2 = {{Chembox Properties | Formula = C13H18ClF3N2O | MolarMass = 310.74 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Mabuterol is a selective β2 adrenoreceptor agonist.[1][2] References1. ^{{cite journal|last1=Osada|first1=E|last2=Murai|first2=T|last3=Ishizaka|first3=Y|last4=Sanai|first4=K|title=Pharmacological studies of mabuterol, a new selective beta 2-stimulant. II: Effects on the cardiovascular system and smooth muscle organs.|journal=Arzneimittel-Forschung|date=1984|volume=34|issue=11A|pages=1641–51|pmid=6152157}} {{Adrenergic agonists}}{{amine-stub}}2. ^{{cite journal |vauthors=Akahane K, Furukawa Y, Ogiwara Y, Haniuda M, Chiba S |title=Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog |journal=Br. J. Pharmacol. |volume=97 |issue=3 |pages=709–16 |date=July 1989 |pmid=2474351 |pmc=1854580 |doi= 10.1111/j.1476-5381.1989.tb12007.x|url=}} 6 : Alcohols|Aromatic amines|Chloroarenes|Trifluoromethyl compounds|Phenethylamines|Tert-butyl compounds |
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