| 释义 |
- References
- Further reading
{{Infobox_gene}}Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase is an enzyme that in humans is encoded by the MAN1B1 gene.[1][2][3]{{PBB_Summary
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}}References1. ^{{cite journal |vauthors=Gonzalez DS, Karaveg K, Vandersall-Nairn AS, Lal A, Moremen KW | title = Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis | journal = J Biol Chem | volume = 274 | issue = 30 | pages = 21375–86 |date=Aug 1999 | pmid = 10409699 | pmc = | doi =10.1074/jbc.274.30.21375 }}
2. ^{{cite journal |vauthors=Tremblay LO, Herscovics A | title = Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis | journal = Glycobiology | volume = 9 | issue = 10 | pages = 1073–8 |date=Nov 1999 | pmid = 10521544 | pmc = | doi =10.1093/glycob/9.10.1073 }}
3. ^{{cite web | title = Entrez Gene: MAN1B1 mannosidase, alpha, class 1B, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11253| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Land A, Braakman I |title=Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum. |journal=Biochimie |volume=83 |issue= 8 |pages= 783–90 |year= 2001 |pmid= 11530211 |doi=10.1016/S0300-9084(01)01314-1 }}
- {{cite journal |vauthors=Dedera DA, Gu RL, Ratner L |title=Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function. |journal=Virology |volume=187 |issue= 1 |pages= 377–82 |year= 1992 |pmid= 1736542 |doi=10.1016/0042-6822(92)90331-I }}
- {{cite journal |vauthors=Kalyanaraman VS, Rodriguez V, Veronese F, etal |title=Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1. |journal=AIDS Res. Hum. Retroviruses |volume=6 |issue= 3 |pages= 371–80 |year= 1990 |pmid= 2187500 |doi=10.1089/aid.1990.6.371 }}
- {{cite journal |vauthors=Shimizu H, Tsuchie H, Honma H, etal |title=Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins. |journal=Jpn. J. Med. Sci. Biol. |volume=43 |issue= 3 |pages= 75–87 |year= 1991 |pmid= 2283726 |doi= 10.7883/yoken1952.43.75}}
- {{cite journal |vauthors=Leonard CK, Spellman MW, Riddle L, etal |title=Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. |journal=J. Biol. Chem. |volume=265 |issue= 18 |pages= 10373–82 |year= 1990 |pmid= 2355006 |doi= }}
- {{cite journal |vauthors=Stein BS, Engleman EG |title=Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex. |journal=J. Biol. Chem. |volume=265 |issue= 5 |pages= 2640–9 |year= 1990 |pmid= 2406237 |doi= }}
- {{cite journal |vauthors=Pal R, Hoke GM, Sarngadharan MG |title=Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 9 |pages= 3384–8 |year= 1989 |pmid= 2541446 |doi=10.1073/pnas.86.9.3384 | pmc=287137 }}
- {{cite journal |vauthors=Dewar RL, Vasudevachari MB, Natarajan V, Salzman NP |title=Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport. |journal=J. Virol. |volume=63 |issue= 6 |pages= 2452–6 |year= 1989 |pmid= 2542563 |doi= | pmc=250699 }}
- {{cite journal |vauthors=Kozarsky K, Penman M, Basiripour L, etal |title=Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein. |journal=J. Acquir. Immune Defic. Syndr. |volume=2 |issue= 2 |pages= 163–9 |year= 1989 |pmid= 2649653 |doi= }}
- {{cite journal |vauthors=Robinson WE, Montefiori DC, Mitchell WM |title=Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis. |journal=AIDS Res. Hum. Retroviruses |volume=3 |issue= 3 |pages= 265–82 |year= 1988 |pmid= 2829950 |doi=10.1089/aid.1987.3.265 }}
- {{cite journal |vauthors=Blough HA, Pauwels R, De Clercq E, etal |title=Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins. |journal=Biochem. Biophys. Res. Commun. |volume=141 |issue= 1 |pages= 33–8 |year= 1987 |pmid= 3099781 |doi=10.1016/S0006-291X(86)80330-8 }}
- {{cite journal |vauthors=Montefiori DC, Robinson WE, Mitchell WM |title=Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 23 |pages= 9248–52 |year= 1988 |pmid= 3264072 |doi=10.1073/pnas.85.23.9248 | pmc=282716 }}
- {{cite journal |vauthors=Fenouillet E, Jones I, Powell B, etal |title=Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain. |journal=J. Virol. |volume=67 |issue= 1 |pages= 150–60 |year= 1993 |pmid= 8093218 |doi= | pmc=237347 }}
- {{cite journal |vauthors=Yeh JC, Seals JR, Murphy CI, etal |title=Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system. |journal=Biochemistry |volume=32 |issue= 41 |pages= 11087–99 |year= 1993 |pmid= 8218172 |doi=10.1021/bi00092a019 }}
- {{cite journal |vauthors=Bolmstedt A, Sjölander S, Hansen JE, etal |title=Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=12 |issue= 3 |pages= 213–20 |year= 1996 |pmid= 8673525 |doi= 10.1097/00042560-199607000-00001}}
- {{cite journal |vauthors=Hu H, Shioda T, Moriya C, etal |title=Infectivities of human and other primate lentiviruses are activated by desialylation of the virion surface. |journal=J. Virol. |volume=70 |issue= 11 |pages= 7462–70 |year= 1996 |pmid= 8892864 |doi= | pmc=190813 }}
- {{cite journal |vauthors=Papandreou MJ, Fenouillet E |title=Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation. |journal=FEBS Lett. |volume=406 |issue= 1-2 |pages= 191–5 |year= 1997 |pmid= 9109416 |doi=10.1016/S0014-5793(97)00273-1 }}
- {{cite journal |vauthors=Tremblay LO, Campbell Dyke N, Herscovics A |title=Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha1,2-mannosidase gene involved in N-glycan maturation. |journal=Glycobiology |volume=8 |issue= 6 |pages= 585–95 |year= 1998 |pmid= 9592125 |doi=10.1093/glycob/8.6.585 }}
{{refend}}{{PDB Gallery|geneid=11253}}{{gene-9-stub}} |