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词条 Mangiferin
释义

  1. Natural occurrences

  2. Research

  3. See also

  4. References

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| Name = Mangiferin
| ImageFile = Mangiferin.svg
| ImageName = Chemical structure of mangiferin
| ImageAlt = Chemical structure of mangiferin
| IUPACName = (1S)-1,5-Anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
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| InChI = 1/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1
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Mangiferin is a xanthonoid. This molecule is a glucoside of norathyriol.

Natural occurrences

Mangiferin was first isolated from the leaves and bark of Mangifera indica.[1] It can also be extracted from mango peels and kernels,[2][3] Iris unguicularis,[4] Anemarrhena asphodeloides rhizomes[5] and Bombax ceiba leaves.[6] It is also found in the genera Salacia and Cyclopia.

Among the group of Asplenium hybrids known as the "Appalachian Asplenium complex", mangiferin and isomangiferin are produced only by Asplenium montanum and its hybrid descendants. The distinctive gold-orange fluorescence of these compounds under ultraviolet light has been used to aid in the chromatographic identification of hybrid Aspleniums.[7]

Research

Laboratory studies have identified a variety of potential pharmacology-associated properties of mangiferin, including antimicrobial and antioxidant activities,[8][3] inhibitory effects on type II 5α-reductase in vitro,[9] and gastroprotective[10] and antidiabetic[5] effects in rodents.

See also

  • Euxanthic acid

References

1. ^K. Gorter (April 1922). "SUR LA SUBSTANCE MÈRE DU JAUNE INDIEN", Bulletin du Jardin botanique de Buitenzorg, (in French). Volume 4 Series 3 Issue 2: p. 260–267; [J.C.S. (20 April 1923). "The precursor of Indian-yellow", Chemical Abstracts, (in English), Volume 17 Issue No. 8: p. 1472] – via archive.com
2. ^{{cite journal |author1=Barreto J.C. |author2=Trevisan M.T.S. |author3=Hull W.E. |author4=Erben G. |author5=De Brito E.S. |author6=Pfundstein B. |author7=Würtele G. |author8=Spiegelhalder B. |author9=Owen R.W. | title = Characterization and quantitation of polyphenolic compounds in bark, kernel, leaves, and peel of mango (Mangifera indica L.) | journal = Journal of Agricultural and Food Chemistry | year = 2008 | volume = 56 | issue = 14 | pages = 5599–5610 | doi = 10.1021/jf800738r | pmid = 18558692}}
3. ^{{Cite journal|last=Rajneet K Khurana|first=Rajneet K Khurana|last2=Kaur|first2=Ranjot|last3=Lohan|first3=Shikha|last4=K Singh|first4=Kamalinder|last5=Singh|first5=Bhupinder|date=2016|title=Mangiferin: a promising anticancer bioactive|url=https://www.future-science.com/doi/10.4155/ppa-2016-0003|journal=PHARMACEUTICAL PATENT ANALYST|volume=5|issue=3|pages=|doi=|via=Future science}}
4. ^{{cite journal | doi = 10.3987/COM-10-S(E)6 | title = New and Known Constituents from Iris unguicularis and Their Antoioxidant Activity | year = 2010 | last1 = Atta-Ur-Rahman | first1 = _ | last2 = Hareem | first2 = Sumaira | last3 = Iqbal Choudhary | first3 = Muhammad | last4 = Sener | first4 = Bilge | last5 = Abbaskhan | first5 = Ahmed | last6 = Siddiqui | first6 = Hina | last7 = Anjum | first7 = Shazia | last8 = Orhan | first8 = Ilkay | last9 = Gurbuz | first9 = Ilhan | last10 = Ayanoglu | first10 = Filiz | journal = Heterocycles | volume = 82 | pages = 813}}
5. ^{{Cite journal | doi = 10.1078/0944-7113-00009 | last1 = Miura | first1 = T. | last2 = Ichiki | first2 = H. | last3 = Hashimoto | first3 = I. | last4 = Iwamoto | first4 = N. | last5 = Kato | first5 = M. | last6 = Kubo | first6 = M. | last7 = Ishihara | first7 = E. | last8 = Komatsu | first8 = Y. | last9 = Okada | first9 = M. | last10 = Ishida | first10 = T. | last11 = Tanigawa | first11 = K. | title = Antidiabetic Activity of a Xanthone Compound, Mangiferin | journal = Phytomedicine | volume = 8 | issue = 2 | pages = 85–87 | year = 2001 | pmid = 11315760}}
6. ^{{cite journal | pmid=15802793 | year=2005 | author1=Dar | first1=A | title=Analgesic and antioxidant activity of mangiferin and its derivatives: The structure activity relationship | journal=Biological & Pharmaceutical Bulletin | volume=28 | issue=4 | pages=596–600 | last2=Faizi | first2=S | last3=Naqvi | first3=S | last4=Roome | first4=T | last5=Zikr-Ur-Rehman | first5=S | last6=Ali | first6=M | last7=Firdous | first7=S | last8=Moin | first8=S. T. | doi=10.1248/bpb.28.596}}
7. ^{{cite journal | last1=Smith | first1=Dale M. | last2=Harborne | first2=Jeffrey B. | authorlink2=Jeffrey Harborne | title=Xanthones in the Appalachian Asplenium complex | journal=Phytochemistry | volume=10 | issue=9 | year=1971 | pages=2117–2119 | doi=10.1016/S0031-9422(00)97205-4}}
8. ^{{ cite journal | title = Antimicrobial and Antioxidant Activity of the Polyphenol Mangiferin |author1=Stoilova, I. |author2=Gargova, S. |author3=Stoyanova, A. |author4=Ho, L. | journal = Herba Polonica | volume = 51 | issue = 1/2 | year = 2005 | issn = 0018-0599 | pages = 37–44 }}
9. ^{{Cite journal | last1 = Wang | first1 = X. | last2 = Liao | first2 = J. | last3 = Yin | first3 = D. | last4 = Zhan | first4 = F. | last5 = Dai | first5 = S. | last6 = Xie | first6 = G. | last7 = Sang | first7 = X. | title = Establishment of a Novel Model for Studying the Effects of Extracts of Chinese Herb Medicine on Human Type II 5-alpha-Reductase in Vitro | journal = Yakugaku Zasshi | volume = 130 | issue = 9 | pages = 1207–1214 | year = 2010 | pmid = 20823678 | doi=10.1248/yakushi.130.1207}}
10. ^{{Cite journal | last1 = Carvalho | first1 = A. | last2 = Guedes | first2 = M. | last3 = De Souza | first3 = A. | last4 = Trevisan | first4 = M. | last5 = Lima | first5 = A. | last6 = Santos | first6 = F. V. | last7 = Rao | first7 = V. | doi = 10.1055/s-2007-990231 | title = Gastroprotective Effect of Mangiferin, a Xanthonoid from Mangifera indica, against Gastric Injury Induced by Ethanol and Indomethacin in Rodents | journal = Planta Medica | volume = 73 | issue = 13 | pages = 1372–1376 | year = 2007 | pmid = 17918041 | pmc = }}
{{xanthone}}

2 : Xanthonoids|C-glycoside natural phenols

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