| 词条 | MARC1 |
| 释义 |
| Name = MOCO sulphurase C-terminal domain containing 1 | caption = | image = | width = | HGNCid = 26189 | Symbol = MOSC1 | AltSymbols = | EntrezGene = 64757 | OMIM = | RefSeq = NM_022746 | UniProt = Q5VT66 | PDB = | ECnumber = | Chromosome = 1 | Arm = q | Band = 41 | LocusSupplementaryData = }}Mitochondrial amidoxime-reducing component 1 (also known as MOCO sulphurase C-terminal domain containing 1, MOSC1 or MARC1) is an enzyme which in humans is encoded by the MOSC1 gene.[1] Moco stands for molybdenum cofactor. MOSC1 has been reported to reduce amidoximes to amidines.[2][3] See also
References1. ^{{cite journal |vauthors=Anantharaman V, Aravind L | title = MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases | journal = FEMS Microbiol. Lett. | volume = 207 | issue = 1 | pages = 55–61 |date=January 2002 | pmid = 11886751 | doi = 10.1016/S0378-1097(01)00515-8 | url = }} {{gene-1-stub}}2. ^{{cite journal |vauthors=Havemeyer A, Bittner F, Wollers S, Mendel R, Kunze T, Clement B | title = Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme | journal = J. Biol. Chem. | volume = 281 | issue = 46 | pages = 34796–802 |date=November 2006 | pmid = 16973608 | doi = 10.1074/jbc.M607697200 | url = }} 3. ^{{cite journal |vauthors=Gruenewald S, Wahl B, Bittner F, Hungeling H, Kanzow S, Kotthaus J, Schwering U, Mendel RR, Clement B | title = The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs | journal = J. Med. Chem. | volume = 51 | issue = 24 | pages = 8173–7 |date=December 2008 | pmid = 19053771 | doi = 10.1021/jm8010417 | url = }} |
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