Mary James may refer to:

• Mary James (educator) (born 1946), Associate Director of Research at the University of Cambridge
• Mary James (scientist), American physicist
• Mary-Dulany James (born 1960), U.S. politician in Maryland
• Mary James, a pen name for author Marijane Meaker, who writes books for young children
• HMS Mary James, two ships of the Royal Navy have borne the name HMS Mary James

• Mad Hatter (Batman 1966)
• Mad Hatter chess
• Mad Hatter DC
• Madhatter's Bliss
• Mad hatter syndrome
• Madhaul Khurd
• Madhaul Khurd (village)
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• Madhavan Balaji Ranganathan
• Madhavan Chandradathan
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• Madhavan, Iran
• Madhavan K. Palat
• Madhavan Nair & Anor. v. Public Prosecutor
• Madhavan r
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• Madhava Perumal temple
• Madhavaram botanical garden
• Madhavaram Botanical Garden
• Madhavaram Krishna Rao
• Madhavaram krishna rao
• Madhavaram Lake
• Madhavaram (state assembly constituency)