Mehmet of Karaman may mean;

• Karamanoğlu Mehmet Bey (reigned 1261–1277) bey of Karamanid Principality.
• Mehmet II of Karaman (reigned 1402–1423) bey of Karamanid Principality.
• Karamani Mehmed Pasha (in office 1478-1481) grand vizier of the Ottoman Empire

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