| 释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Homeobox protein Meis2 is a protein that in humans is encoded by the MEIS2 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.[3]
}}References1. ^{{cite journal |vauthors=Smith JE, Afonja O, Yee HT, Inghirami G, Takeshita K | title = Chromosomal mapping to 15q14 and expression analysis of the human MEIS2 homeobox gene | journal = Mamm Genome | volume = 8 | issue = 12 | pages = 951–2 |date=Jan 1998 | pmid = 9383298 | pmc = | doi =10.1007/s003359900621 }}
2. ^{{cite web | title = Entrez Gene: MEIS2 Meis homeobox 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4212| accessdate = }}
3. ^{{cite web | title = Entrez Gene: MEIS2 Meis homeobox 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4212| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Hui H, Perfetti R |title=Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood. |journal=Eur. J. Endocrinol. |volume=146 |issue= 2 |pages= 129–41 |year= 2002 |pmid= 11834421 |doi=10.1530/eje.0.1460129 }}
- {{cite journal |vauthors=Steelman S, Moskow JJ, Muzynski K, etal |title=Identification of a conserved family of Meis1-related homeobox genes. |journal=Genome Res. |volume=7 |issue= 2 |pages= 142–56 |year= 1997 |pmid= 9049632 |doi=10.1101/gr.7.2.142 }}
- {{cite journal |vauthors=Capdevila J, Tsukui T, Rodríquez Esteban C, etal |title=Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin. |journal=Mol. Cell |volume=4 |issue= 5 |pages= 839–49 |year= 2000 |pmid= 10619030 |doi=10.1016/S1097-2765(00)80393-7 }}
- {{cite journal |vauthors=Yang Y, Hwang CK, D'Souza UM, etal |title=Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription. |journal=J. Biol. Chem. |volume=275 |issue= 27 |pages= 20734–41 |year= 2000 |pmid= 10764806 |doi= 10.1074/jbc.M908382199 }}
- {{cite journal |vauthors=Liu Y, MacDonald RJ, Swift GH |title=DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex. |journal=J. Biol. Chem. |volume=276 |issue= 21 |pages= 17985–93 |year= 2001 |pmid= 11279116 |doi= 10.1074/jbc.M100678200 }}
- {{cite journal |vauthors=Fujino T, Yamazaki Y, Largaespada DA, etal |title=Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes. |journal=Exp. Hematol. |volume=29 |issue= 7 |pages= 856–63 |year= 2001 |pmid= 11438208 |doi=10.1016/S0301-472X(01)00655-5 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Dintilhac A, Bihan R, Guerrier D, etal |title=A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis. |journal=Gene Expr. Patterns |volume=4 |issue= 2 |pages= 215–22 |year= 2004 |pmid= 15161102 |doi= 10.1016/j.modgep.2003.08.006 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
{{refend}} External links - {{MeshName|MEIS2+protein,+human}}
{{NLM content}}{{Transcription factors|g3}}{{gene-15-stub}} 1 : Transcription factors |