词条 | Meseclazone |
释义 |
| IUPAC_name = 7-chloro-2-methyl-3,3a-dihydro-2H,9H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one | image = Meseclazone.png | tradename = | pregnancy_category = | legal_status = Uncontrolled | routes_of_administration = Oral | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number = 29053-27-8 | ATC_prefix = none | ATC_suffix = | PubChem = 34445 | ChemSpiderID = 31698 | ChEMBL = 2104738 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 51KFT71THG | KEGG = D04941 | C=11 | H=10 | Cl=1 | N=1 | O=3 | molecular_weight = 239.66 g/mol | smiles = Clc2cc1C(=O)N3OC(CC3Oc1cc2)C }}Meseclazone (W-2395), also known as 2-methylseclazone, is a nonsteroidal anti-inflammatory drug (NSAID) developed in the 1970s.[1][2] It functions as a prodrug to the 5-chloro derivative of salicyclic acid.[3] It was never marketed on account of toxicity issues, namely pertaining to the liver.[4] See also
References1. ^{{cite book | author = | title = Dictionary of organic compounds | publisher = Chapman & Hall | location = London | year = 1996 | pages = | isbn = 0-412-54090-8 | oclc = | doi = | url = https://books.google.com/books?id=r7z8W69GcoMC&lpg=PA4167&dq=Meseclazone&pg=PA4167#v=onepage&q&f=false}} {{NSAIDs}}{{Analgesics}}2. ^{{cite book | author = Rainsford, K. D. | title = Aspirin and related drugs | publisher = Taylor & Francis | location = Washington, DC | year = 2004 | pages = | isbn = 0-7484-0885-1 | oclc = | doi = | url = https://books.google.com/books?id=9xYuQKZSDkIC&lpg=PA67&dq=Meseclazone&pg=PA67#v=onepage&q&f=false}} 3. ^{{cite book | author = Rainsford, K. D. | title = Aspirin and related drugs | publisher = Taylor & Francis | location = Washington, DC | year = 2004 | pages = | isbn = 0-7484-0885-1 | oclc = | doi = | url = https://books.google.com/books?id=9xYuQKZSDkIC&lpg=PA67&dq=Meseclazone&pg=PA67#v=onepage&q&f=false}} 4. ^{{cite book | author = Rainsford, K. D. | title = Aspirin and related drugs | publisher = Taylor & Francis | location = Washington, DC | year = 2004 | pages = | isbn = 0-7484-0885-1 | oclc = | doi = | url = https://books.google.com/books?id=9xYuQKZSDkIC&lpg=PA67&dq=Meseclazone&pg=PA67#v=onepage&q&f=false}} 2 : Analgesics|Nonsteroidal anti-inflammatory drugs |
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