“Methenyltetrahydromethanopterin cyclohydrolase”的意思、由来-开放百科全书

词条

Methenyltetrahydromethanopterin cyclohydrolase

释义

References

{{enzyme
| Name = methenyltetrahydromethanopterin cyclohydrolase
| EC_number = 3.5.4.27
| CAS_number = 99533-50-3
| IUBMB_EC_number = 3/5/4/27
| GO_code = 0018759
| image = 4gvq.jpg
| width = 270
| caption = Methenyltetrahydromethanopterin cyclohydrolase trimer, Archaeoglobus fulgidus
}}

In enzymology, a methenyltetrahydromethanopterin cyclohydrolase ({{EC number|3.5.4.27}}) is an enzyme that catalyzes the chemical reaction

5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H₂O 5-formyl-5,6,7,8-tetrahydromethanopterin

Thus, the two substrates of this enzyme are 5,10-methenyl-5,6,7,8-tetrahydromethanopterin and H₂O, whereas its product is 5-formyl-5,6,7,8-tetrahydromethanopterin.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing). Other names in common use include 5,10-methenyltetrahydromethanopterin cyclohydrolase, N5,N10-methenyltetrahydromethanopterin cyclohydrolase, and methenyl-H4MPT cyclohydrolase. This enzyme participates in folate biosynthesis.

References

{{cite journal |vauthors=Donnelly MI, Escalante-Semerena JC, Rinehart KL, Wolfe RS | date = 1985 | title = Methenyl-tetrahydromethanopterin cyclohydrolase in cell extracts of Methanobacterium | journal = Arch. Biochem. Biophys. | volume = 242 | pages = 430–9 | pmid = 4062290 | doi = 10.1016/0003-9861(85)90227-9 | issue = 2 }}

{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{3.5-enzyme-stub}}

2 : EC 3.5.4|Enzymes of unknown structure

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