| 词条 | Methimepip |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 360227021 | ImageFile=Methimepip.svg | ImageSize= | IUPACName=4-(1H-imidazol-4-ylmethyl)-1-methylpiperidine | OtherNames= |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=151070-80-3 | PubChem=11313837 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 175782 | IUPHAR_ligand = 1254 | SMILES=CN1CCC(CC1)CC2=CN=CN2 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 9488804 | InChI = 1/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12) | InChIKey = KIAVPENCSGKVQP-UHFFFAOYAQ | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = KIAVPENCSGKVQP-UHFFFAOYSA-N | RTECS = | MeSHName = C500075 |Section2={{Chembox Properties | Formula=C10H17N3 | MolarMass=179.262 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}Methimepip is a histamine agonist which is highly selective for the H3 subtype. It is the N-methyl derivative of immepip.[1] References1. ^{{cite journal |vauthors=Kitbunnadaj R, Hashimoto T, Poli E, etal |title=N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist |journal=Journal of Medicinal Chemistry |volume=48 |issue=6 |pages=2100–7 |date=March 2005 |pmid=15771452 |doi=10.1021/jm049475h}} {{Histaminergics}}{{pharma-stub}} 3 : Imidazoles|Histamine agonists|Piperidines |
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