| 词条 | Mitobronitol |
| 释义 |
| ImageFile = Mitobronitol.png | ImageFile_Ref = {{chemboximage|correct|??}} | ImageSize = 160 | ImageName = Stereo, skeletal formula of mitobronitol (2S,3S,4S,5S)-2,3,4,5-tetrol | PIN = 1,6-Dibromo-1,6-dideoxy-D-mannitol{{Citation needed|date=June 2012}} | SystematicName = 1,6-Dibromohexane-2,3,4,5-tetrol[1] |Section1={{Chembox Identifiers | CASNo = 488-41-5 | CASNo_Ref = {{cascite|correct|??}} | CASNo_Comment = (2S,3S,4S,5S)-2,3,4,5-tetrol | PubChem = 4208 | PubChem1 = 44119013 | PubChem1_Comment = (2R,3R)-2,3-diol | PubChem2 = 6713087 | PubChem2_Comment = (2S,3S,5R)-2,3,5-triol | PubChem3 = 2794952 | PubChem3_Comment = (2R,3R,4R,5R)-2,3,4,5-tetrol | PubChem4 = 656655 | PubChem4_Comment = (2S,3S,4S,5S)-2,3,4,5-tetrol | ChemSpiderID = 4063 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID1 = 5145112 | ChemSpiderID1_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID1_Comment = (2S,3S,5R)-2,3,5-triol | ChemSpiderID2 = 5145112 | ChemSpiderID2_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID2_Comment = (2R,3R,4R,5R)-2,3,4,5-tetrol | UNII = 5UP30YED7N | UNII_Ref = {{fdacite|correct|FDA}} | EINECS = 207-676-8 | KEGG = D02020 | KEGG_Ref = {{keggcite|correct|kegg}} | MeSHName = Mitobronitol | ChEMBL = 161657 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL1 = 447629 | ChEMBL1_Ref = {{ebicite|correct|EBI}} | RTECS = OP2800000 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol | SMILES = OC(CBr)C(O)C(O)C(O)CBr | StdInChI = 1S/C6H12Br2O4/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,9-12H,1-2H2 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = VFKZTMPDYBFSTM-UHFFFAOYSA-N | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} }} |Section2={{Chembox Properties | C=6 | H=12 | Br=2 | O=4 | Appearance = Colourless crystals | pKa = 12.609 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol | pKb = 1.388 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol | LogP = −0.226 (2RS,3RS,4RS,5RS)-2,3,4,5-tetrol }} |Section6={{Chembox Pharmacology | ATCCode_prefix = L01 | ATCCode_suffix = AX01 }} |Section8={{Chembox Related | OtherCompounds = {{Unbulleted list|1,2-Dibromopropane|1,3-Dibromopropane|1,2,3-Tribromopropane}} }} }}Mitobronitol (1,6-dibromo-1,6-dideoxy-D-mannitol) is a brominated analog of mannitol. It is an anticancer drug that is classified as an alkylating agent.[2] References1. ^{{Cite web|title=Mitolactol - Compound Summary|url=https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=4208&loc=ec_rcs|work=PubChem Compound|publisher=National Center for Biotechnology Information|accessdate=22 June 2012|location=USA|date=25 March 2005|at=Identification}} {{Intracellular chemotherapeutic agents}}{{Antineoplastic-drug-stub}}2. ^Mitobronitol, The Centre for Cancer Education 4 : Organobromides|DNA replication inhibitors|Monosaccharide derivatives|Halohydrins |
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