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词条 MKL2
释义

  1. References

  2. Further reading

{{Infobox_gene}}MKL/myocardin-like protein 2 is a protein that in humans is encoded by the MKL2 gene.[1][2]

Members of the myocardin family bind to the transcription factor serum response factor (SRF) and act as coactivators controlling genes of relevance for myogenic differentiation and motile function. [3]

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References

1. ^{{cite journal |vauthors=Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 6 | issue = 5 | pages = 337–45 |date=Jan 2000 | pmid = 10574462 | pmc = | doi =10.1093/dnares/6.5.337 }}
2. ^{{cite web | title = Entrez Gene: MKL2 MKL/myocardin-like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57496| accessdate = }}
3. ^{{cite journal |vauthors=Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O | title = Emerging roles of the myocardin family of proteins in lipid and glucose metabolism | journal = J Physiol | volume = 594 | issue = 17 | pages = 4741–4752 |date=September 2016 | pmid = 27060572 | pmc = 5009794 | doi = 10.1113/JP271913 }}

Further reading

{{refbegin | 2}}
  • {{cite journal |vauthors=Nakajima D, Okazaki N, Yamakawa H, etal |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99 }}
  • {{cite journal |vauthors=Wang DZ, Li S, Hockemeyer D, etal |title=Potentiation of serum response factor activity by a family of myocardin-related transcription factors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 23 |pages= 14855–60 |year= 2003 |pmid= 12397177 |doi= 10.1073/pnas.222561499 | pmc=137508 }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
  • {{cite journal |vauthors=Cen B, Selvaraj A, Burgess RC, etal |title=Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. |journal=Mol. Cell. Biol. |volume=23 |issue= 18 |pages= 6597–608 |year= 2003 |pmid= 12944485 |doi=10.1128/MCB.23.18.6597-6608.2003 | pmc=193697 }}
  • {{cite journal |vauthors=Selvaraj A, Prywes R |title=Megakaryoblastic leukemia-1/2, a transcriptional co-activator of serum response factor, is required for skeletal myogenic differentiation. |journal=J. Biol. Chem. |volume=278 |issue= 43 |pages= 41977–87 |year= 2004 |pmid= 14565952 |doi= 10.1074/jbc.M305679200 }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
  • {{cite journal |vauthors=Morita T, Mayanagi T, Sobue K |title=Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. |journal=J. Cell Biol. |volume=179 |issue= 5 |pages= 1027–42 |year= 2007 |pmid= 18056415 |doi= 10.1083/jcb.200708174 | pmc=2099179 }}
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