| 释义 |
- Interactions
- References
- Further reading
- External links
{{Infobox_gene}}Protein ENL is a protein that in humans is encoded by the MLLT1 gene.[1] Interactions MLLT1 has been shown to interact with CBX8.[2] References 1. ^{{cite web | title = Entrez Gene: MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4298| accessdate = }}
2. ^{{cite journal | vauthors = García-Cuéllar MP, Zilles O, Schreiner SA, Birke M, Winkler TH, Slany RK | title = The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3 | journal = Oncogene | volume = 20 | issue = 4 | pages = 411–9 | date = January 2001 | pmid = 11313972 | doi = 10.1038/sj.onc.1204108 }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Tkachuk DC, Kohler S, Cleary ML | title = Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias | journal = Cell | volume = 71 | issue = 4 | pages = 691–700 | date = November 1992 | pmid = 1423624 | doi = 10.1016/0092-8674(92)90602-9 }}
- {{cite journal | vauthors = Thirman MJ, Levitan DA, Kobayashi H, Simon MC, Rowley JD | title = Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 91 | issue = 25 | pages = 12110–4 | date = December 1994 | pmid = 7991593 | pmc = 45386 | doi = 10.1073/pnas.91.25.12110 }}
- {{cite journal | vauthors = Rubnitz JE, Morrissey J, Savage PA, Cleary ML | title = ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells | journal = Blood | volume = 84 | issue = 6 | pages = 1747–52 | date = September 1994 | pmid = 8080983 | doi = }}
- {{cite journal | vauthors = Yamamoto K, Seto M, Komatsu H, Iida S, Akao Y, Kojima S, Kodera Y, Nakazawa S, Ariyoshi Y, Takahashi T | title = Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia | journal = Oncogene | volume = 8 | issue = 10 | pages = 2617–25 | date = October 1993 | pmid = 8378076 | doi = }}
- {{cite journal | vauthors = Lavau C, Luo RT, Du C, Thirman MJ | title = Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 20 | pages = 10984–9 | date = September 2000 | pmid = 10995463 | pmc = 27135 | doi = 10.1073/pnas.190167297 }}
- {{cite journal | vauthors = García-Cuéllar MP, Zilles O, Schreiner SA, Birke M, Winkler TH, Slany RK | title = The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3 | journal = Oncogene | volume = 20 | issue = 4 | pages = 411–9 | date = January 2001 | pmid = 11313972 | doi = 10.1038/sj.onc.1204108 }}
- {{cite journal | vauthors = Nie Z, Yan Z, Chen EH, Sechi S, Ling C, Zhou S, Xue Y, Yang D, Murray D, Kanakubo E, Cleary ML, Wang W | title = Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner | journal = Molecular and Cellular Biology | volume = 23 | issue = 8 | pages = 2942–52 | date = April 2003 | pmid = 12665591 | pmc = 152562 | doi = 10.1128/MCB.23.8.2942-2952.2003 }}
- {{cite journal | vauthors = Gué M, Sun JS, Boudier T | title = Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited | journal = BMC Cancer | volume = 6 | pages = 20 | date = January 2006 | pmid = 16433901 | pmc = 1388228 | doi = 10.1186/1471-2407-6-20 }}
- {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = November 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
- {{cite journal | vauthors = Meyer C, Burmeister T, Strehl S, Schneider B, Hubert D, Zach O, Haas O, Klingebiel T, Dingermann T, Marschalek R | title = Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia | journal = Leukemia | volume = 21 | issue = 3 | pages = 588–90 | date = March 2007 | pmid = 17252016 | doi = 10.1038/sj.leu.2404542 }}
{{refend}} External links - {{MeshName|MLLT1+protein,+human}}
{{NLM content}}{{Transcription factors|g0}}{{gene-19-stub}} 1 : Transcription factors |