| 释义 |
- Function
- See also
- References
- Further reading
{{Infobox_gene}}Mps one binder kinase activator-like 1A, also known as Mob1 homolog 1A, is a protein that in humans is encoded by the MOBKL1A gene.[1][2] Function The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation.[1] See also References1. ^1 {{cite web | title = Entrez Gene: MOB1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92597| accessdate = }}
2. ^{{cite journal |vauthors=Devroe E, Erdjument-Bromage H, Tempst P, Silver PA | title = Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases | journal = J. Biol. Chem. | volume = 279 | issue = 23 | pages = 24444–51 |date=June 2004 | pmid = 15067004 | doi = 10.1074/jbc.M401999200 | url = | issn = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928}}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1996 |pmid= 8889548 |doi= 10.1101/gr.6.9.791}}
- {{cite journal |vauthors=Bichsel SJ, Tamaskovic R, Stegert MR, Hemmings BA |title=Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein. |journal=J. Biol. Chem. |volume=279 |issue= 34 |pages= 35228–35 |year= 2004 |pmid= 15197186 |doi= 10.1074/jbc.M404542200 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241}}
- {{cite journal |vauthors=Chow A, Hao Y, Yang X |title=Molecular characterization of human homologs of yeast MOB1. |journal=Int. J. Cancer |volume=126 |issue= 9 |pages= 2079–89 |year= 2010 |pmid= 19739119 |doi= 10.1002/ijc.24878 }}
{{refend}}{{PDB Gallery|geneid=92597}}{{Hippo signaling pathway}}{{NLM content}}{{gene-4-stub}} |