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词条 Lipoamide
释义

  1. See also

  2. References

{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 429966421
| ImageFile = Lipoamide-2D-skeletal.png
| ImageName = Skeletal formula
| ImageFile1 = Lipoamide-3D-vdW.png
| ImageName1 = Space-filling model
| IUPACName = 5-(1,2-Dithiolan-3-yl)pentanamide
| OtherNames =
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 5360246
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 17460
| InChI = 1/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10)/t7-/m1/s1
| InChIKey = FCCDDURTIIUXBY-SSDOTTSWBG
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10)/t7-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = FCCDDURTIIUXBY-SSDOTTSWSA-N
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 940-69-2
| PubChem = 6992093
| SMILES = O=C(N)CCCC[C@H]1SSCC1
| MeSHName = lipoamide
|Section2={{Chembox Properties
| C=8 | H=15 | N=1 | O=1 | S=2
| MolarMass = 205.343 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}

Lipoamide is a trivial name for 6,8-dithiooctanoic amide. It is 6,8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an amide linkage (containing -NH2).[1] Sometimes lipoamide is used to refer to protein bound lipoic acid, but this can be misleading as this is technically incorrect. Lipoyl-protein or lipoyl-domain are better terms to refer to protein bound lipoic acid.

There are no reported occurrences of free lipoamide in nature.

See also

  • Lipoic acid

References

1. ^{{Cite web | url = http://www.hmdb.ca/metabolites/HMDB0000962 | title = Metabocard for Lipoamide | work = Human Metabolome Database}}
{{Organic-compound-stub}}

2 : Organic disulfides|Carboxamides

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