Motygino ({{lang-ru|Мотыгино}}) is the name of several inhabited localities in Russia.

Urban localities

• Motygino, Krasnoyarsk Krai, a work settlement in Motyginsky District of Krasnoyarsk Krai

Rural localities

• Motygino, Pskov Oblast, a village in Sebezhsky District of Pskov Oblast
• Motygino, Yaroslavl Oblast, a village in Yermakovsky Rural Okrug of Lyubimsky District of Yaroslavl Oblast

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