释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Multiple PDZ domain protein is a protein that in humans is encoded by the MPDZ gene.[1] Interactions MPDZ has been shown to interact with: - 5-HT2C receptor,[2][3]
- CD117,[4] and
- PLEKHA1.[5]
References 1. ^{{cite web | title = Entrez Gene: MPDZ multiple PDZ domain protein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8777| accessdate = }} 2. ^{{cite journal | vauthors = Becamel C, Figge A, Poliak S, Dumuis A, Peles E, Bockaert J, Lubbert H, Ullmer C | title = Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1 | journal = J. Biol. Chem. | volume = 276 | issue = 16 | pages = 12974–82 | date = April 2001 | pmid = 11150294 | doi = 10.1074/jbc.M008089200 }} 3. ^{{cite journal | vauthors = Ullmer C, Schmuck K, Figge A, Lübbert H | title = Cloning and characterization of MUPP1, a novel PDZ domain protein | journal = FEBS Lett. | volume = 424 | issue = 1-2 | pages = 63–8 | date = March 1998 | pmid = 9537516 | doi = 10.1016/s0014-5793(98)00141-0}} 4. ^{{cite journal | vauthors = Mancini A, Koch A, Stefan M, Niemann H, Tamura T | title = The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity | journal = FEBS Lett. | volume = 482 | issue = 1-2 | pages = 54–8 | date = September 2000 | pmid = 11018522 | doi = 10.1016/s0014-5793(00)02036-6}} 5. ^{{cite journal | vauthors = Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR | title = Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo | journal = Biochem. J. | volume = 361 | issue = Pt 3 | pages = 525–36 | date = February 2002 | pmid = 11802782 | pmc = 1222335 | doi = 10.1042/0264-6021:3610525}}
Further reading {{refbegin|35em}}- {{cite journal | vauthors = Ullmer C, Schmuck K, Figge A, Lübbert H | title = Cloning and characterization of MUPP1, a novel PDZ domain protein | journal = FEBS Lett. | volume = 424 | issue = 1–2 | pages = 63–8 | year = 1998 | pmid = 9537516 | doi = 10.1016/S0014-5793(98)00141-0 }}
- {{cite journal | vauthors = Barritt DS, Pearn MT, Zisch AH, Lee SS, Javier RT, Pasquale EB, Stallcup WB | title = The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2 | journal = J. Cell. Biochem. | volume = 79 | issue = 2 | pages = 213–24 | year = 2000 | pmid = 10967549 | pmc = 3501957 | doi = 10.1002/1097-4644(20001101)79:2<213::AID-JCB50>3.0.CO;2-G }}
- {{cite journal | vauthors = Lee SS, Glaunsinger B, Mantovani F, Banks L, Javier RT | title = Multi-PDZ Domain Protein MUPP1 Is a Cellular Target for both Adenovirus E4-ORF1 and High-Risk Papillomavirus Type 18 E6 Oncoproteins | journal = J. Virol. | volume = 74 | issue = 20 | pages = 9680–93 | year = 2000 | pmid = 11000240 | pmc = 112400 | doi = 10.1128/JVI.74.20.9680-9693.2000 }}
- {{cite journal | vauthors = Mancini A, Koch A, Stefan M, Niemann H, Tamura T | title = The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity | journal = FEBS Lett. | volume = 482 | issue = 1–2 | pages = 54–8 | year = 2000 | pmid = 11018522 | doi = 10.1016/S0014-5793(00)02036-6 }}
- {{cite journal | vauthors = Becamel C, Figge A, Poliak S, Dumuis A, Peles E, Bockaert J, Lubbert H, Ullmer C | title = Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1 | journal = J. Biol. Chem. | volume = 276 | issue = 16 | pages = 12974–82 | year = 2001 | pmid = 11150294 | doi = 10.1074/jbc.M008089200 }}
- {{cite journal | vauthors = Vassilev A, Kaneko KJ, Shu H, Zhao Y, DePamphilis ML | title = TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm | journal = Genes Dev. | volume = 15 | issue = 10 | pages = 1229–41 | year = 2001 | pmid = 11358867 | pmc = 313800 | doi = 10.1101/gad.888601 }}
- {{cite journal | vauthors = Hamazaki Y, Itoh M, Sasaki H, Furuse M, Tsukita S | title = Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule | journal = J. Biol. Chem. | volume = 277 | issue = 1 | pages = 455–61 | year = 2002 | pmid = 11689568 | doi = 10.1074/jbc.M109005200 }}
- {{cite journal | vauthors = Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR | title = Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo | journal = Biochem. J. | volume = 361 | issue = Pt 3 | pages = 525–36 | year = 2002 | pmid = 11802782 | pmc = 1222335 | doi = 10.1042/0264-6021:3610525 }}
- {{cite journal | vauthors = Poliak S, Matlis S, Ullmer C, Scherer SS, Peles E | title = Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells | journal = J. Cell Biol. | volume = 159 | issue = 2 | pages = 361–72 | year = 2002 | pmid = 12403818 | pmc = 2173042 | doi = 10.1083/jcb.200207050 }}
- {{cite journal | vauthors = Griffon N, Jeanneteau F, Prieur F, Diaz J, Sokoloff P | title = CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors | journal = Brain Res. Mol. Brain Res. | volume = 117 | issue = 1 | pages = 47–57 | year = 2003 | pmid = 14499480 | doi = 10.1016/S0169-328X(03)00283-3 }}
- {{cite journal | vauthors = Krapivinsky G, Medina I, Krapivinsky L, Gapon S, Clapham DE | title = SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation | journal = Neuron | volume = 43 | issue = 4 | pages = 563–74 | year = 2004 | pmid = 15312654 | doi = 10.1016/j.neuron.2004.08.003 }}
- {{cite journal | vauthors = van de Pavert SA, Kantardzhieva A, Malysheva A, Meuleman J, Versteeg I, Levelt C, Klooster J, Geiger S, Seeliger MW, Rashbass P, Le Bivic A, Wijnholds J | title = Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure | journal = J. Cell Sci. | volume = 117 | issue = Pt 18 | pages = 4169–77 | year = 2005 | pmid = 15316081 | doi = 10.1242/jcs.01301 }}
- {{cite journal | vauthors = Coyne CB, Voelker T, Pichla SL, Bergelson JM | title = The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction | journal = J. Biol. Chem. | volume = 279 | issue = 46 | pages = 48079–84 | year = 2005 | pmid = 15364909 | doi = 10.1074/jbc.M409061200 }}
- {{cite journal | vauthors = Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW | title = Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux | journal = J. Biol. Chem. | volume = 280 | issue = 47 | pages = 39653–64 | year = 2006 | pmid = 16192269 | doi = 10.1074/jbc.M510187200 }}
- {{cite journal | vauthors = Heydecke D, Meyer D, Ackermann F, Wilhelm B, Gudermann T, Boekhoff I | title = The multi PDZ domain protein MUPP1 as a putative scaffolding protein for organizing signaling complexes in the acrosome of mammalian spermatozoa | journal = J. Androl. | volume = 27 | issue = 3 | pages = 390–404 | year = 2006 | pmid = 16452527 | doi = 10.2164/jandrol.05166 }}
- {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
- {{cite journal | vauthors = Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M | title = Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns | journal = Genome Biology | volume = 8 | issue = 8 | pages = R154 | year = 2007 | pmid = 17672918 | pmc = 2374985 | doi = 10.1186/gb-2007-8-8-r154 }}
{{refend}}{{PDB Gallery|geneid=8777}}{{gene-9-stub}} |