“MRPS25”的意思、由来-开放百科全书

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MRPS25

释义

References
Further reading

{{Infobox_gene}}28S ribosomal protein S25, mitochondrial is a protein that in humans is encoded by the MRPS25 gene.^[1]^[2]{{PBB_Summary
| section_title =
| summary_text = Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4.^[2]
}}

References

1. ^{{cite journal |vauthors=Cavdar Koc E, Burkhart W, Blackburn K, Moseley A, Spremulli LL | title = The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present | journal = J Biol Chem | volume = 276 | issue = 22 | pages = 19363–74 |date=May 2001 | pmid = 11279123 | pmc = | doi = 10.1074/jbc.M100727200 }}
2. ^¹{{cite web | title = Entrez Gene: MRPS25 mitochondrial ribosomal protein S25| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64432| accessdate = }}

{{cite journal | author=Ewing RM |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 |name-list-format=vanc| author2=Chu P | author3=Elisma F | display-authors=3 | last4=Li | first4=Hongyan | last5=Taylor | first5=Paul | last6=Climie | first6=Shane | last7=McBroom-Cerajewski | first7=Linda | last8=Robinson | first8=Mark D | last9=O'Connor | first9=Liam }}
{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
{{cite journal |vauthors=Zhang Z, Gerstein M |title=Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome |journal=Genomics |volume=81 |issue= 5 |pages= 468–80 |year= 2003 |pmid= 12706105 |doi=10.1016/S0888-7543(03)00004-1 }}
{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
{{cite journal | author=Kenmochi N |title=The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders |journal=Genomics |volume=77 |issue= 1–2 |pages= 65–70 |year= 2001 |pmid= 11543634 |doi= 10.1006/geno.2001.6622 |name-list-format=vanc| author2=Suzuki T | author3=Uechi T | display-authors=3 | last4=Magoori | first4=Mika | last5=Kuniba | first5=Mariko | last6=Higa | first6=Sayomi | last7=Watanabe | first7=Kimitsuna | last8=Tanaka | first8=Tatsuo }}
{{cite journal | author=Hattori A |title=Characterization of long cDNA clones from human adult spleen |journal=DNA Res. |volume=7 |issue= 6 |pages= 357–66 |year= 2001 |pmid= 11214971 |doi=10.1093/dnares/7.6.357 |name-list-format=vanc| author2=Okumura K | author3=Nagase T | display-authors=3 | last4=Kikuno | first4=R | last5=Hirosawa | first5=M | last6=Ohara | first6=O }}
{{cite journal | author=Koc EC |title=A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32585–91 |year= 2000 |pmid= 10938081 |doi= 10.1074/jbc.M003596200 |name-list-format=vanc| author2=Burkhart W | author3=Blackburn K | display-authors=3 | last4=Moseley | first4=A | last5=Koc | first5=H | last6=Spremulli | first6=LL }}

1 : Ribosomal proteins

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