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词条 List of chemotherapeutic agents
释义

  1. Alkylating agents

  2. Anthracyclines

  3. Cytoskeletal disruptors (taxanes)

  4. Epothilones

  5. Histone deacetylase inhibitors

  6. Inhibitors of topoisomerase I

  7. Inhibitors of topoisomerase II

  8. Kinase inhibitors

  9. Nucleotide analogs and precursor analogs

  10. Peptide antibiotics

  11. Platinum-based agents

  12. Retinoids

  13. Vinca alkaloids and derivatives

  14. Full alphabetical listing

  15. Comprehensive table

This is a list of chemotherapeutic agents (also known as cytotoxic agents) that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, hydroxydaunorubicin (doxorubicin), vincristine (Oncovin), and prednisone.

Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.

Alkylating agents

{{Main article|Alkylating agent}}Bifunctional alkylators
  • Cyclophosphamide
  • Mechlorethamine
  • Chlorambucil
  • Melphalan
Monofunctional alkylators
  • Dacarbazine
  • Nitrosoureas
  • Temozolomide(Oral dacarbazine)

Anthracyclines

{{Main article|anthracycline}}
  • Daunorubicin
  • Doxorubicin
  • Epirubicin
  • Idarubicin
  • Mitoxantrone
  • Valrubicin

Cytoskeletal disruptors (taxanes)

{{Main article|Taxane}}
  • Paclitaxel
  • Docetaxel
  • Abraxane
  • Taxotere

Epothilones

{{Main article|epothilone}}

Histone deacetylase inhibitors

  • Vorinostat
  • Romidepsin

Inhibitors of topoisomerase I

{{Main article|Topoisomerase inhibitor}}
  • Irinotecan
  • Topotecan

Inhibitors of topoisomerase II

{{Main article|Topoisomerase II inhibitor}}
  • Etoposide
  • Teniposide
  • Tafluposide

Kinase inhibitors

{{Main article|Kinase inhibitor}}
  • Bortezomib
  • Erlotinib
  • Gefitinib
  • Imatinib
  • Vemurafenib
  • Vismodegib

Nucleotide analogs and precursor analogs

  • Azacitidine
  • Azathioprine
  • Capecitabine
  • Cytarabine
  • Doxifluridine
  • Fluorouracil
  • Gemcitabine
  • Hydroxyurea
  • Mercaptopurine
  • Methotrexate
  • Tioguanine (formerly Thioguanine)

Peptide antibiotics

{{main article|Antimicrobial peptides}}
  • Bleomycin
  • Actinomycin

Platinum-based agents

{{Main article|Platinum-based antineoplastic}}
  • Carboplatin
  • Cisplatin
  • Oxaliplatin

Retinoids

  • Tretinoin
  • Alitretinoin
  • Bexarotene

Vinca alkaloids and derivatives

{{Main article|Vinca alkaloid}}
  • Vinblastine
  • Vincristine
  • Vindesine
  • Vinorelbine

Full alphabetical listing

{{Col-begin}}{{Col-3}}
  • Actinomycin
  • All-trans retinoic acid
  • Azacitidine
  • Azathioprine
  • Bleomycin
  • Bortezomib
  • Carboplatin
  • Capecitabine
  • Cisplatin
  • Chlorambucil
  • Cyclophosphamide
  • Cytarabine
  • Daunorubicin
  • Docetaxel
{{Col-3}}
  • Doxifluridine
  • Doxorubicin
  • Epirubicin
  • Epothilone
  • Etoposide
  • Fluorouracil
  • Gemcitabine
  • Hydroxyurea
  • Idarubicin
  • Imatinib
  • Irinotecan
  • Mechlorethamine
  • Mercaptopurine
{{Col-3}}
  • Methotrexate
  • Mitoxantrone
  • Oxaliplatin
  • Paclitaxel
  • Pemetrexed
  • Teniposide
  • Tioguanine
  • Topotecan
  • Valrubicin
  • Vemurafenib
  • Vinblastine
  • Vincristine
  • Vindesine
{{Col-End}}

Comprehensive table

{{Intracellular chemotherapeutic agents}}Chemotherapie#Klassieke cytostatica

1 : Antineoplastic drugs

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