“MTX1”的意思、由来-开放百科全书

The metaxin gene, which encodes a protein located on the outer membrane of mitochondria, is a component of the mitochondrial protein translocation apparatus.^[3]

References

1. ^{{cite web | title = Entrez Gene: MTX1 metaxin 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4580| accessdate = }}
2. ^{{cite journal |vauthors=Bornstein P, McKinney CE, LaMarca ME, Winfield S, Shingu T, Devarayalu S, Vos HL, Ginns EI | title = Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 92 | issue = 10 | pages = 4547–51 |date=May 1995 | pmid = 7753840 | pmc = 41981 | doi = 10.1073/pnas.92.10.4547| url = http://www.pnas.org/cgi/pmidlookup?view=long&pmid=7753840 }}
3. ^{{cite journal |vauthors=Armstrong LC, Komiya T, Bergman BE, Mihara K, Bornstein P | title = Metaxin is a component of a preprotein import complex in the outer membrane of the mammalian mitochondrion | journal = J. Biol. Chem. | volume = 272 | issue = 10 | pages = 6510–8 |date=March 1997 | pmid = 9045676 | doi = 10.1074/jbc.272.10.6510| url = http://www.jbc.org/cgi/pmidlookup?view=long&pmid=9045676 }}

Further reading

{{cite journal | author=Bornstein P |title=Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 10 |pages= 4547–51 |year= 1995 |pmid= 7753840 |doi=10.1073/pnas.92.10.4547 | pmc=41981 |name-list-format=vanc| author2=McKinney CE | author3=LaMarca ME | display-authors=3 | last4=Winfield | first4=S | last5=Shingu | first5=T | last6=Devarayalu | first6=S | last7=Vos | first7=HL | last8=Ginns | first8=EI }}

{{cite journal | author=Long GL |title=Structure and organization of the human metaxin gene (MTX) and pseudogene |journal=Genomics |volume=33 |issue= 2 |pages= 177–84 |year= 1997 |pmid= 8660965 |doi= 10.1006/geno.1996.0181 |name-list-format=vanc| author2=Winfield S | author3=Adolph KW | display-authors=3 | last4=Ginns | first4=Edward I. | last5=Bornstein | first5=Paul }}

{{cite journal | author=Armstrong LC |title=Metaxin is a component of a preprotein import complex in the outer membrane of the mammalian mitochondrion |journal=J. Biol. Chem. |volume=272 |issue= 10 |pages= 6510–8 |year= 1997 |pmid= 9045676 |doi=10.1074/jbc.272.10.6510 |name-list-format=vanc| author2=Komiya T | author3=Bergman BE | display-authors=3 | last4=Mihara | first4=K | last5=Bornstein | first5=P }}

{{cite journal | author=Winfield SL |title=Identification of Three Additional Genes Contiguous to the Glucocerebrosidase Locus on Chromosome 1q21: Implications for Gaucher Disease |journal=Genome Res. |volume=7 |issue= 10 |pages= 1020–6 |year= 1997 |pmid= 9331372 |doi= 10.1101/gr.7.10.1020 | pmc=310674 |name-list-format=vanc| author2=Tayebi N | author3=Martin BM | display-authors=3 | last4=Ginns | first4=EI | last5=Sidransky | first5=E }}

{{cite journal |vauthors=Armstrong LC, Saenz AJ, Bornstein P |title=Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane |journal=J. Cell. Biochem. |volume=74 |issue= 1 |pages= 11–22 |year= 1999 |pmid= 10381257 |doi=10.1002/(SICI)1097-4644(19990701)74:1<11::AID-JCB2>3.0.CO;2-V }}

{{cite journal | author=Abdul KM |title=Functional analysis of human metaxin in mitochondrial protein import in cultured cells and its relationship with the Tom complex |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 3 |pages= 1028–34 |year= 2000 |pmid= 11027586 |doi= 10.1006/bbrc.2000.3589 |name-list-format=vanc| author2=Terada K | author3=Yano M | display-authors=3 | last4=Ryan | first4=Michael T. | last5=Streimann | first5=Illo | last6=Hoogenraad | first6=Nicholas J. | last7=Mori | first7=Masataka }}

{{cite journal | author=Wang X |title=Metaxin is required for tumor necrosis factor-induced cell death |journal=EMBO Rep. |volume=2 |issue= 7 |pages= 628–33 |year= 2001 |pmid= 11454742 |doi= 10.1093/embo-reports/kve135 | pmc=1083949 |name-list-format=vanc| author2=Ono K | author3=Kim SO | display-authors=3 | last4=Kravchenko | first4=Vladimir | last5=Lin | first5=Sheng-Cai | last6=Han | first6=Jiahuai }}

{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}

{{cite journal | author=LaMarca ME |title=A novel alteration in metaxin 1, F202L, is associated with N370S in Gaucher disease |journal=J. Hum. Genet. |volume=49 |issue= 4 |pages= 220–2 |year= 2004 |pmid= 15024629 |doi= 10.1007/s10038-004-0134-7 |name-list-format=vanc| author2=Goldstein M | author3=Tayebi N | display-authors=3 | last4=Arcos-Burgos | first4=Mauricio | last5=Martin | first5=Brian M. | last6=Sidransky | first6=Ellen }}

{{cite journal | author=Ewing RM |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 |name-list-format=vanc| author2=Chu P | author3=Elisma F | display-authors=3 | last4=Li | first4=Hongyan | last5=Taylor | first5=Paul | last6=Climie | first6=Shane | last7=McBroom-Cerajewski | first7=Linda | last8=Robinson | first8=Mark D | last9=O'Connor | first9=Liam }}

{{cite journal | author=Kozjak-Pavlovic V |title=Conserved roles of Sam50 and metaxins in VDAC biogenesis |journal=EMBO Rep. |volume=8 |issue= 6 |pages= 576–82 |year= 2007 |pmid= 17510655 |doi= 10.1038/sj.embor.7400982 | pmc=2002532 |name-list-format=vanc| author2=Ross K | author3=Benlasfer N | display-authors=3 | last4=Kimmig | first4=Sonja | last5=Karlas | first5=Alexander | last6=Rudel | first6=Thomas }}

{{cite journal | author=Xie J |title=The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11 |journal=FEBS Lett. |volume=581 |issue= 18 |pages= 3545–9 |year= 2007 |pmid= 17624330 |doi= 10.1016/j.febslet.2007.06.052 |name-list-format=vanc| author2=Marusich MF | author3=Souda P | display-authors=3 | last4=Whitelegge | first4=Julian | last5=Capaldi | first5=Roderick A. }}