| 词条 | Mutant protein |
| 释义 |
A mutant protein is the protein product encoded by a gene with mutation.[1] Mutated protein can have single amino acid change (minor, but still in many cases significant change leading to disease) or wide-range amino acid changes by e.g. truncation of C-terminus after introducing premature stop codon. See also
References1. ^{{cite journal |first1=Qing |last1=Wang |first2=Raghothama |last2=Chaerkady |first3=Jian |last3=Wu |first4=Hee Jung |last4=Hwang |first5=Nick |last5=Papadopoulos |first6=Levy |last6=Kopelovich |first7=Anirban |last7=Maitra |first8=Hanno |last8=Matthaei |first9=James R. |last10=Hruban |first10=R. H. |last11=Kinzler |first11=K. W. |last12=Pandey |first12=A. |last13=Vogelstein |first13=B. |last9=Eshleman |pages=2444–9 |doi=10.1073/pnas.1019203108 |title=Mutant proteins as cancer-specific biomarkers |year=2011 |journal=Proceedings of the National Academy of Sciences |volume=108 |issue=6 |pmid=21248225 |pmc=3038743|display-authors=8 }} {{protein-stub}} 2 : Proteins|Mutation |
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