词条 | Myrotoxin B |
释义 |
| Watchedfields = changed | verifiedrevid = 428831944 | ImageFile = Myrotoxin B.svg | ImageSize = | IUPACName = | OtherNames = |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 99486-49-4 | PubChem = 6540635 | SMILES = CC1=C[C@]2([H])[C@]([C@@](C)3[C@]4(CO4)[C@@]([H])(C[C@H]3OC5=O)O2)(CO[C@]([C@@H](O7)[C@]([C@H]/6O)7CCOC6=C/C/C=C\\5)=O)C[C@@H]1OC(C)=O }} |Section2={{Chembox Properties | C=29 | H=34 | O=11 | Appearance = | Density = | MeltingPtC = 195 to 197 | MeltingPt_ref = [1] | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Myrotoxin B is a macrocyclic trichothecene first isolated in 1985.[1] It was tested on Swiss mice and found to be very toxic, though not the most toxic of the three toxins that were tested at that time.[2] It has also been isolated from Myrothecium roridum, a pathogen leaf spot that affects mulberry, though it is unknown if it is used as a pathotoxin.[3] References1. ^1 {{cite journal |author1=Jarvis, B. B. |author2=Lee, Y.-W. |author3=Cömezoḡlu, F. T. |author4=Cömezoḡlu, S. N. |author5=Bean, G. A. | title = Myrotoxins: a new class of macrocyclic trichothecenes | journal = Tetrahedron Letters | year = 1985 | volume = 26 | issue = 40 | pages = 4859–62 | doi = 10.1016/S0040-4039(00)94970-0 }} {{Organic-compound-stub}}2. ^{{ cite journal |author1=Schiefer, H. B. |author2=Hancock, D. S. |author3=Jarvis, B. B. | title = Toxicology of Novel Macrocyclic Trichothecenes, Baccharinoid B4, Myrotoxin B, and Roritoxin B | journal = Zentralblatt für Veterinärmedizin. Reihe A | year = 1989 | volume = 36 | issue = 2 | pages = 152–60 | pmid = 2501953 | issn = 0514-7158 }} 3. ^{{ cite journal | title = Myrotoxin B Detection from Mulberry Leaves Infected with Myrothecium roridum, cause Myrothecium Leaf Spot of Mulberry, and Possible Roles in Pathogenicity |author1=Murakami, R. |author2=Shirata, A. | journal = Japanese Journal of Phytopathology | year = 2005 | volume = 71 | issue = 2 | pages = 91–100 | doi = 10.3186/jjphytopath.71.91 | url = https://www.jstage.jst.go.jp/article/jjphytopath1918/71/2/71_2_91/_pdf | format = pdf }} 5 : Trichothecenes|Acetate esters|Lactones|Epoxides|Alcohols |
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