“N6-acetyl-beta-lysine transaminase”的意思、由来-开放百科全书

词条

N6-acetyl-beta-lysine transaminase

释义

References

{{enzyme
| Name = N6-acetyl-beta-lysine transaminase
| EC_number = 2.6.1.65
| CAS_number = 71768-10-0
| IUBMB_EC_number = 2/6/1/65
| GO_code = 0047317
| image =
| width =
| caption =
}}

In enzymology, a N6-acetyl-beta-lysine transaminase ({{EC number|2.6.1.65}}) is an enzyme that catalyzes the chemical reaction

6-acetamido-3-aminohexanoate + 2-oxoglutarate 6-acetamido-3-oxohexanoate + L-glutamate

Thus, the two substrates of this enzyme are 6-acetamido-3-aminohexanoate and 2-oxoglutarate, whereas its two products are 6-acetamido-3-oxohexanoate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase. This enzyme is also called epsilon-acetyl-beta-lysine aminotransferase. This enzyme participates in lysine degradation. It employs one cofactor, pyridoxal phosphate.

References

{{cite journal | vauthors = Bozler G, Robertson JM, Ohsugi M, Hensley C, Barker HA | date = 1979 | title = Metabolism of L-beta-lysine in a Pseudomonas: conversion of 6-N-acetyl-L-beta-lysine to 3-keto-6-acetamidohexanoate and of 4-aminobutyrate to succinic semialdehyde by different transaminases | journal = Arch. Biochem. Biophys. | volume = 197 | pages = 226–35 | pmid = 44448 | doi = 10.1016/0003-9861(79)90240-6 | issue = 1 }}

3 : EC 2.6.1|Pyridoxal phosphate enzymes|Enzymes of unknown structure

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