| 词条 | Nadrian Seeman |
| 释义 |
| name = Nadrian C. Seeman | image = Nadrian Seeman.jpg | image_size = | alt = | caption = | birth_date = {{birth date and age|1945|12|16}} | birth_place = | death_date = | death_place = | residence = | citizenship = | nationality = | fields = Nanotechnology, Crystallography | workplaces = New York University | alma_mater = University of Chicago, University of Pittsburgh | doctoral_advisor = | academic_advisors = | doctoral_students = | notable_students = | known_for = DNA nanotechnology | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = Kavli Prize in Nanoscience {{small|(2010)}} Benjamin Franklin Medal in Chemistry {{small|(2016)}} | signature = | signature_alt = | footnotes = }}Nadrian C. "Ned" Seeman (born December 16, 1945) is an American nanotechnologist and crystallographer known for inventing the field of DNA nanotechnology.[1][1] Seeman studied biochemistry at the University of Chicago and crystallography at the University of Pittsburgh.[2] He became a faculty member at the State University of New York at Albany, and in 1988 moved to the Department of Chemistry at New York University. He is most noted for his development of the concept of DNA nanotechnology beginning in the early 1980s.[3] In fall 1980, while at a campus pub, Seeman was inspired by the M. C. Escher woodcut Depth to realize that a three-dimensional lattice could be constructed from DNA. He realized that this could be used to orient target molecules, simplifying their crystallographic study by eliminating the difficult process of obtaining pure crystals.[4][5] In pursuit of this goal, Seeman's laboratory published the synthesis of the first three-dimensional nanoscale object, a cube made of DNA, in 1991. This work won the 1995 Feynman Prize in Nanotechnology.[6] The concept of the dissimilar double DNA crossover introduced by Seeman,[7] was important stepping stone towards the development of DNA origami. The concepts of DNA nanotechnology later found further applications in DNA computing,[8] DNA nanorobotics, and self-assembly of nanoelectronics.[10] He shared the Kavli Prize in Nanoscience 2010 with Donald Eigler “for their development of unprecedented methods to control matter on the nanoscale.”[9][10] The goal of demonstrating designed three-dimensional DNA crystals was achieved by Seeman in 2009, nearly thirty years after his original elucidation of the idea. He is a fellow of the Norwegian Academy of Science and Letters[11] He is an atheist.[12] Notable publications
See also
References1. ^{{cite news |title=8 Scientists Share $3 Million in Prizes |author=Dennis Overbye |newspaper=The New York Times |date=3 June 2010 |url=https://www.nytimes.com/2010/06/04/science/04kavli.html}} 2. ^{{cite web |url=http://seemanlab4.chem.nyu.edu/Seeman.html |publisher=Nadrian Seeman lab |title=Ned's Biography}} 3. ^1 {{cite book |last=Pelesko |first=John A. |title=Self-assembly: the science of things that put themselves together |year=2007 |publisher=Chapman & Hall/CRC |location=New York |isbn=978-1-58488-687-7 |pages=201, 242, 259}} 4. ^{{cite journal |last=Seeman |first=Nadrian C. |title=Nanotechnology and the double helix |journal=Scientific American |date=June 2004 |pages=64–75 |pmid=15195395 |url=https://www.scientificamerican.com/article/nanotechnology-and-the-double-helix/ |volume=290 |issue=6 |doi=10.1038/scientificamerican0604-64}} 5. ^See Nadrian Seeman's homepage, Current crystallization protocol for a statement of the problem, and Nadrian Seeman's homepage, DNA cages containing oriented guests for the proposed solution. 6. ^{{cite web |url=http://www.foresight.org/Updates/Update23/Update23.1.html#anchor415574 |publisher=The Foresight Institute |title=1995 Feynman Prize in Nanotechnology Awarded For Pioneering Synthesis of 3-D DNA Objects |date=30 November 1995}} 7. ^{{cite journal|last1=Fu|first1=Tsu-Ju|last2=Seeman|first2=Nadrian|title=DNA Double-Crossover Molecules|journal=Biochemistry|date=1993|volume=32|pages=3211–3220|doi=10.1021/bi00064a003}} 8. ^{{cite journal| last1=Ng | first1=W. D. | last2=Wong | first2=C. K. B. |title=Self-Recognition of DNA: From Life Processes to DNA Computation|journal=Biophysical Reviews and Letters|volume=2|issue=2|pages=123–137|year=2007| doi=10.1142/S1793048007000490 | pmid=20640192 | pmc=2905173}} 9. ^1 {{cite web |url=http://www.nyu.edu/about/news-publications/news/2010/06/03/nyu-chemist-seeman-wins-kavli-prize-in-nanoscience-.html |publisher=New York University |title=NYU Chemist Seeman Wins Kavli Prize in Nanoscience |date=3 June 2010}} 10. ^{{cite web |url=http://www.kavliprize.no/nyheter/vis.html?tid=46747 |publisher=The Kavli Prize |title=Names of the 2010 Kavli Prize winners announced}} 11. ^{{cite web|url=http://www.dnva.no/c26849/artikkel/vis.html?tid=40122|title=Gruppe 4: Kjemi|publisher=Norwegian Academy of Science and Letters|language=Norwegian|accessdate=30 March 2016}} 12. ^http://www.kavliprize.org. N.p., n.d. Web. 05 Oct. 2016. "At about the time I got to high school, I lost whatever faith I might have had, and I've been an atheist ever since." 13. ^{{Cite journal | last1 = Pinheiro | first1 = A. V. | last2 = Han | first2 = D. | last3 = Shih | first3 = W. M. | last4 = Yan | first4 = H. | title = Challenges and opportunities for structural DNA nanotechnology | journal = Nature Nanotechnology | volume = 6 | issue = 12 | pages = 763–772 | date=December 2011 | pmid = 22056726 | pmc = 3334823 | doi = 10.1038/nnano.2011.187}} External links
11 : Living people|Crystallographers|American atheists|New York University faculty|University of Chicago alumni|University of Pittsburgh alumni|DNA nanotechnology people|University at Albany, SUNY faculty|1945 births|Guggenheim Fellows|Members of the Norwegian Academy of Science and Letters |
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