请输入您要查询的百科知识:

 

词条 Naked cuticle 2
释义

  1. Sources

Naked cuticle 2 (NKD2) is a human gene that encodes the protein Nkd2, one of the Naked cuticle (Nkd) family of proteins that regulate the Wnt signaling pathway.[1][2] Both Nkd1 and Nkd2 proteins can bind to Dishevelled proteins (DVL1, DVL2, DVL3), but only Nkd2 can bind to the EGF-ligand family member TGF alpha and regulate its polarized secretion in cultured epithelial cells.[3]

Sources

1. ^{{cite journal | last1 = Wharton | first1 = KA Jr | last2 = Zimmermann | first2 = G | last3 = Rousset | first3 = R | last4 = Scott | first4 = MP | date = Jun 2001 | title = Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling | url = | journal = Dev. Biol. | volume = 234 | issue = 1| pages = 93–106 | doi = 10.1006/dbio.2001.0238 | pmid = 11356022 }}
2. ^{{cite journal | last1 = Katoh | first1 = M | date = Nov 2001 | title = Molecular cloning, gene structure, and expression analyses of NKD1 and NKD2 | url = | journal = Int J Oncol | volume = 19 | issue = 5| pages = 963–9 | pmid = 11604995 | doi=10.3892/ijo.19.5.963}}
3. ^{{cite journal | last1 = Li | first1 = C | last2 = Franklin | first2 = JL | last3 = Graves-Deal | first3 = R | last4 = Jerome | first4 = WG | last5 = Cao | first5 = Z | last6 = Coffey | first6 = RJ | date = Apr 2004 | title = Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells | url = | journal = Proc Natl Acad Sci U S A | volume = 101 | issue = 15| pages = 5571–6 | doi = 10.1073/pnas.0401294101 | pmid = 15064403 | pmc=397424}}

1 : Human proteins

随便看

 

开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。

 

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间:2024/11/10 14:55:47