释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene.[1][2] NCR1 has also been designated as CD335 (cluster of differentiation, NKP46, NKp46, NK-p46, and LY94.[3]References1. ^{{cite journal |vauthors=Pessino A, Sivori S, Bottino C, Malaspina A, Morelli L, Moretta L, Biassoni R, Moretta A | title = Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity | journal = J Exp Med | volume = 188 | issue = 5 | pages = 953–60 |date=Sep 1998 | pmid = 9730896 | pmc = 3207313| doi =10.1084/jem.188.5.953 }} 2. ^{{cite web | title = Entrez Gene: NCR1 natural cytotoxicity triggering receptor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9437| accessdate = }} 3. ^https://www.ncbi.nlm.nih.gov/gene/9437
Further reading{{refbegin | 2}}- {{cite journal | author=Biassoni R |title=Human natural killer cell receptors: insights into their molecular function and structure |journal=J. Cell. Mol. Med. |volume=7 |issue= 4 |pages= 376–87 |year= 2004 |pmid= 14754506 |doi=10.1111/j.1582-4934.2003.tb00240.x |name-list-format=vanc| author2=Cantoni C | author3=Marras D | display-authors=3 | last4=Giron-Michel | first4=J. | last5=Falco | first5=Michela | last6=Moretta | first6=L. | last7=Dimasi | first7=N. }}
- {{cite journal | author=Sivori S |title=p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation |journal=J. Exp. Med. |volume=186 |issue= 7 |pages= 1129–36 |year= 1997 |pmid= 9314561 |doi=10.1084/jem.186.7.1129 | pmc=2211712 |name-list-format=vanc| author2=Vitale M | author3=Morelli L | display-authors=3 | last4=Sanseverino | first4=L | last5=Augugliaro | first5=R | last6=Bottino | first6=C | last7=Moretta | first7=L | last8=Moretta | first8=A }}
- {{cite journal | author=Vitale M |title=NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis |journal=J. Exp. Med. |volume=187 |issue= 12 |pages= 2065–72 |year= 1998 |pmid= 9625766 |doi=10.1084/jem.187.12.2065 | pmc=2212362 |name-list-format=vanc| author2=Bottino C | author3=Sivori S | display-authors=3 | last4=Sanseverino | first4=L | last5=Castriconi | first5=R | last6=Marcenaro | first6=E | last7=Augugliaro | first7=R | last8=Moretta | first8=L | last9=Moretta | first9=A }}
- {{cite journal | author=Cantoni C |title=NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin Superfamily |journal=J. Exp. Med. |volume=189 |issue= 5 |pages= 787–96 |year= 1999 |pmid= 10049942 |doi=10.1084/jem.189.5.787 | pmc=2192947 |name-list-format=vanc| author2=Bottino C | author3=Vitale M | display-authors=3 | last4=Pessino | first4=A | last5=Augugliaro | first5=R | last6=Malaspina | first6=A | last7=Parolini | first7=S | last8=Moretta | first8=L | last9=Moretta | first9=A }}
- {{cite journal | author=Vankayalapati R |title=The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium |journal=J. Immunol. |volume=168 |issue= 7 |pages= 3451–7 |year= 2002 |pmid= 11907104 |doi= 10.4049/jimmunol.168.7.3451|name-list-format=vanc| author2=Wizel B | author3=Weis SE | display-authors=3 | last4=Safi | first4=H | last5=Lakey | first5=DL | last6=Mandelboim | first6=O | last7=Samten | first7=B | last8=Porgador | first8=A | last9=Barnes | first9=PF }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
- {{cite journal | author=Augugliaro R |title=Selective cross-talk among natural cytotoxicity receptors in human natural killer cells |journal=Eur. J. Immunol. |volume=33 |issue= 5 |pages= 1235–41 |year= 2003 |pmid= 12731048 |doi= 10.1002/eji.200323896 |name-list-format=vanc| author2=Parolini S | author3=Castriconi R | display-authors=3 | last4=Marcenaro | first4=Emanuela | last5=Cantoni | first5=Claudia | last6=Nanni | first6=Marina | last7=Moretta | first7=Lorenzo | last8=Moretta | first8=Alessandro | last9=Bottino | first9=Cristina }}
- {{cite journal | author=Ponassi M |title=Structure of the human NK cell triggering receptor NKp46 ectodomain |journal=Biochem. Biophys. Res. Commun. |volume=309 |issue= 2 |pages= 317–23 |year= 2003 |pmid= 12951052 |doi=10.1016/j.bbrc.2003.08.007 |name-list-format=vanc| author2=Cantoni C | author3=Biassoni R | display-authors=3 | last4=Conte | first4=Romana | last5=Spallarossa | first5=Andrea | last6=Pesce | first6=Alessandra | last7=Moretta | first7=Alessandro | last8=Moretta | first8=Lorenzo | last9=Bolognesi | first9=Martino }}
- {{cite journal |vauthors=Foster CE, Colonna M, Sun PD |title=Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptors |journal=J. Biol. Chem. |volume=278 |issue= 46 |pages= 46081–6 |year= 2003 |pmid= 12960161 |doi= 10.1074/jbc.M308491200 }}
- {{cite journal | author=Arnon TI |title=The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46 |journal=Blood |volume=103 |issue= 2 |pages= 664–72 |year= 2004 |pmid= 14504081 |doi= 10.1182/blood-2003-05-1716 |name-list-format=vanc| author2=Achdout H | author3=Lieberman N | display-authors=3 | last4=Gazit | first4=R | last5=Gonen-Gross | first5=T | last6=Katz | first6=G | last7=Bar-Ilan | first7=A | last8=Bloushtain | first8=N | last9=Lev | first9=M }}
- {{cite journal | author=Marcenaro E |title=CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity |journal=Eur. J. Immunol. |volume=33 |issue= 12 |pages= 3367–76 |year= 2004 |pmid= 14635045 |doi= 10.1002/eji.200324425 |name-list-format=vanc| author2=Augugliaro R | author3=Falco M | display-authors=3 | last4=Castriconi | first4=Roberta | last5=Parolini | first5=Silvia | last6=Sivori | first6=Simona | last7=Romeo | first7=Elisa | last8=Millo | first8=Romano | last9=Moretta | first9=Lorenzo }}
- {{cite journal | author=Carbone E |title=HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells |journal=Blood |volume=105 |issue= 1 |pages= 251–8 |year= 2005 |pmid= 15328155 |doi= 10.1182/blood-2004-04-1422 |name-list-format=vanc| author2=Neri P | author3=Mesuraca M | display-authors=3 | last4=Fulciniti | first4=MT | last5=Otsuki | first5=T | last6=Pende | first6=D | last7=Groh | first7=V | last8=Spies | first8=T | last9=Pollio | first9=G }}
- {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal |vauthors=Mavoungou E, Bouyou-Akotet MK, Kremsner PG |title=Effects of prolactin and cortisol on natural killer (NK) cell surface expression and function of human natural cytotoxicity receptors (NKp46, NKp44 and NKp30) |journal=Clin. Exp. Immunol. |volume=139 |issue= 2 |pages= 287–96 |year= 2005 |pmid= 15654827 |doi= 10.1111/j.1365-2249.2004.02686.x | pmc=1809301 }}
- {{cite journal | author=Nowbakht P |title=Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias |journal=Blood |volume=105 |issue= 9 |pages= 3615–22 |year= 2005 |pmid= 15657183 |doi= 10.1182/blood-2004-07-2585 |name-list-format=vanc| author2=Ionescu MC | author3=Rohner A | display-authors=3 | last4=Kalberer | first4=CP | last5=Rossy | first5=E | last6=Mori | first6=L | last7=Cosman | first7=D | last8=De Libero | first8=G | last9=Wodnar-Filipowicz | first9=A }}
- {{cite journal | author=Poggi A |title=Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors |journal=J. Immunol. |volume=174 |issue= 5 |pages= 2653–60 |year= 2005 |pmid= 15728472 |doi= 10.4049/jimmunol.174.5.2653|name-list-format=vanc| author2=Massaro AM | author3=Negrini S | display-authors=3 | last4=Contini | first4=P | last5=Zocchi | first5=MR }}
- {{cite journal | author=Zilka A |title=Characterization of the heparin/heparan sulfate binding site of the natural cytotoxicity receptor NKp46 |journal=Biochemistry |volume=44 |issue= 44 |pages= 14477–85 |year= 2006 |pmid= 16262248 |doi= 10.1021/bi051241s |name-list-format=vanc| author2=Landau G | author3=Hershkovitz O | display-authors=3 | last4=Bloushtain | first4=Noga | last5=Bar-Ilan | first5=Ahuva | last6=Benchetrit | first6=Fabrice | last7=Fima | first7=Eyal | last8=Van Kuppevelt | first8=Toin H. | last9=Gallagher | first9=John T. }}
- {{cite journal | author=Hermann E |title=Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells |journal=Pediatr. Res. |volume=60 |issue= 1 |pages= 38–43 |year= 2006 |pmid= 16690951 |doi= 10.1203/01.pdr.0000220335.05588.ea |name-list-format=vanc| author2=Alonso-Vega C | author3=Berthe A | display-authors=3 | last4=Truyens | first4=Carine | last5=Flores | first5=Amilcar | last6=Cordova | first6=Marisol | last7=Moretta | first7=Lorenzo | last8=Torrico | first8=Faustino | last9=Braud | first9=Veronique }}
{{refend}}{{PDB Gallery|geneid=9437}}External links- {{MeshName|NCR1+protein,+human}}
{{Clusters of differentiation}}{{DEFAULTSORT:Ncr1}} 2 : Clusters of differentiation|Human proteins |