| 释义 |
- References
- Further reading
{{Infobox_gene}}NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial is an enzyme that in humans is encoded by the NDUFV3 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.[2]
}}References1. ^{{cite journal | vauthors = de Coo RF, Buddiger P, Smeets HJ, van Oost BA | title = Molecular cloning and characterization of the human mitochondrial NADH:oxidoreductase 10-kDa gene (NDUFV3) | journal = Genomics | volume = 45 | issue = 2 | pages = 434–7 |date=Feb 1998 | pmid = 9344673 | pmc = | doi = 10.1006/geno.1997.4930 | url = http://repub.eur.nl/pub/57339 }}
2. ^1 {{cite web | title = Entrez Gene: NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4731| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Sled VD, Vinogradov AD |title=Kinetics of the mitochondrial NADH-ubiquinone oxidoreductase interaction with hexammineruthenium(III). |journal=Biochim. Biophys. Acta |volume=1141 |issue= 2–3 |pages= 262–8 |year= 1993 |pmid= 8443212 |doi=10.1016/0005-2728(93)90051-G }}
- {{cite journal | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
- {{cite journal |vauthors=Loeffen JL, Triepels RH, van den Heuvel LP, etal |title=cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed |journal=Biochem. Biophys. Res. Commun. |volume=253 |issue= 2 |pages= 415–22 |year= 1999 |pmid= 9878551 |doi= 10.1006/bbrc.1998.9786 }}
- {{cite journal |vauthors=Scanlan MJ, Gordan JD, Williamson B, etal |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456–64 |year= 1999 |pmid= 10508479 |doi=10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 }}
- {{cite journal |vauthors=Hattori M, Fujiyama A, Taylor TD, etal |title=The DNA sequence of human chromosome 21 |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518 }}
- {{cite journal |vauthors=Berry A, Scott HS, Kudoh J, etal |title=Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region |journal=Genomics |volume=68 |issue= 1 |pages= 22–9 |year= 2001 |pmid= 10950923 |doi= 10.1006/geno.2000.6253 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal | vauthors=Zakharova NV, Zharova TV |title=Kinetic mechanism of mitochondrial NADH:ubiquinone oxidoreductase interaction with nucleotide substrates of the transhydrogenase reaction |journal=Biochemistry Mosc. |volume=67 |issue= 12 |pages= 1395–404 |year= 2003 |pmid= 12600270 |doi=10.1023/A:1021818312040 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Kervinen M, Hinttala R, Helander HM, etal |title=The MELAS mutations 3946 and 3949 perturb the critical structure in a conserved loop of the ND1 subunit of mitochondrial complex I |journal=Hum. Mol. Genet. |volume=15 |issue= 17 |pages= 2543–52 |year= 2006 |pmid= 16849371 |doi= 10.1093/hmg/ddl176 }}
{{refend}}{{gene-21-stub}} 1 : Human proteins |