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词条 N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
释义

  1. References

{{DISPLAYTITLE:N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline}}{{chembox
| Watchedfields = changed
| verifiedrevid = 424811563
| Reference =[1]
| Name = N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
| ImageFile =EEDQ.png
| ImageSize =
| IUPACName =2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester
| OtherNames =Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
|Section1={{Chembox Identifiers
| Abbreviations = EEDQ
| CASNo_Ref = {{cascite|correct|??}}
| CASNo =16357-59-8
| PubChem =27833
| SMILES =CCOC1C=CC2=CC=CC=C2N1C(=O)OCC
|Section2={{Chembox Properties
| Formula =C14H17NO3
| MolarMass =247.29 g/mol
| Appearance =
| Density =
| MeltingPtC = 62 to 67
| MeltingPt_notes =
| BoilingPt =
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]

EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]

References

1. ^2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline at Sigma-Aldrich
2. ^Neuroscience Letters 1992, 137(2), p.265
3. ^https://www.bachem.com/bachem/bachem/joust/index.cfm?idland=223
{{Dopamine antagonists}}{{DEFAULTSORT:Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, N-}}{{heterocyclic-stub}}

3 : Carbamates|Quinolines|Ethers

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