| 词条 | Neuromedin S |
| 释义 |
| Name = Neuromedin S | caption = | image = | width = | HGNCid = 32203 | Symbol = NMS | AltSymbols = | EntrezGene = 129521 | OMIM = | RefSeq = | UniProt = | PDB = | ECnumber = | Chromosome = 2 | Arm = q | Band = 11.2 | LocusSupplementaryData = }}Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian rhythm and also has appetite suppressant effects,[1][2][3][4][5] as well as regulating the release of several other peptide hormones including vasopressin,[6] luteinizing hormone,[7] and oxytocin.[8] See also
References1. ^{{cite journal |vauthors=Mori K, Miyazato M, Ida T, Murakami N, Serino R, Ueta Y, Kojima M, Kangawa K |title=Identification of neuromedin S and its possible role in the mammalian circadian oscillator system |journal=The EMBO Journal |volume=24 |issue=2 |pages=325–35 |date=January 2005 |pmid=15635449 |pmc=545815 |doi=10.1038/sj.emboj.7600526 |url=}} {{Neuropeptides}}2. ^{{cite journal |vauthors=Mori K, Miyazato M, Kangawa K |title=Neuromedin S: discovery and functions |journal=Results and Problems in Cell Differentiation |volume=46 |issue= |pages=201–12 |year=2008 |pmid=18214396 |doi=10.1007/400_2007_054 |url=}} 3. ^{{cite journal |author=Novak CM |title=Neuromedin S and U |journal=Endocrinology |volume=150 |issue=7 |pages=2985–7 |date=July 2009 |pmid=19549882 |doi=10.1210/en.2009-0448 |url= |pmc=2703548}} 4. ^{{cite journal |vauthors=Peier A, Kosinski J, Cox-York K, Qian Y, Desai K, Feng Y, Trivedi P, Hastings N, Marsh DJ |title=The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2) |journal=Endocrinology |volume=150 |issue=7 |pages=3101–9 |date=July 2009 |pmid=19324999 |doi=10.1210/en.2008-1772 |url= |pmc=2703546}} 5. ^{{cite journal |vauthors=Mitchell J, Maguire J, Davenport A |title=Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S |journal=British Journal of Pharmacology |volume= 158|issue= 1|pages= 87–103|date=June 2009 |pmid=19519756 |doi=10.1111/j.1476-5381.2009.00252.x |url= |pmc=2795236}} 6. ^{{cite journal |vauthors=Sakamoto T, Mori K, Nakahara K, Miyazato M, Kangawa K, Sameshima H, Murakami N |title=Neuromedin S exerts an antidiuretic action in rats |journal=Biochemical and Biophysical Research Communications |volume=361 |issue=2 |pages=457–61 |date=September 2007 |pmid=17645872 |doi=10.1016/j.bbrc.2007.07.036 |url=}} 7. ^{{cite journal |vauthors=Vigo E, Roa J, López M, Castellano JM, Fernandez-Fernandez R, Navarro VM, Pineda R, Aguilar E, Diéguez C, Pinilla L, Tena-Sempere M |title=Neuromedin s as novel putative regulator of luteinizing hormone secretion |journal=Endocrinology |volume=148 |issue=2 |pages=813–23 |date=February 2007 |pmid=17110433 |doi=10.1210/en.2006-0636 |url=}} 8. ^{{cite journal |vauthors=Sakamoto T, Mori K, Miyazato M, Kangawa K, Sameshima H, Nakahara K, Murakami N |title=Involvement of neuromedin S in the oxytocin release response to suckling stimulus |journal=Biochemical and Biophysical Research Communications |volume=375 |issue=1 |pages=49–53 |date=October 2008 |pmid=18675786 |doi=10.1016/j.bbrc.2008.07.124 |url=}} 1 : Neuropeptides |
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