| 释义 |
- Interactions
- References
- Further reading
- External links
{{Infobox_gene}} __NOTOC__Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene.[1][2]It is involved in megakaryocyte production.[3] Interactions NFE2 has been shown to interact with CREB-binding protein.[4] References 1. ^{{cite journal | vauthors = Ney PA, Andrews NC, Jane SM, Safer B, Purucker ME, Weremowicz S, Morton CC, Goff SC, Orkin SH, Nienhuis AW | title = Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner | journal = Mol Cell Biol | volume = 13 | issue = 9 | pages = 5604–12 | date = Sep 1993 | pmid = 8355703 | pmc = 360284 | doi = 10.1128/mcb.13.9.5604}}
2. ^{{cite web | title = Entrez Gene: NFE2 nuclear factor (erythroid-derived 2), 45kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4778| accessdate = }}
3. ^{{cite journal | vauthors = Gasiorek JJ, Blank V |title = Regulation and function of the NFE2 transcription factor in hematopoietic and non-hematopoietic cells | journal = Cellular and Molecular Life Sciences | volume = 72 | issue = 12 | pages = 2323–2335 | date = 2015 | doi=10.1007/s00018-015-1866-6 | pmid=25721735}}
4. ^{{cite journal | vauthors = Hung HL, Kim AY, Hong W, Rakowski C, Blobel GA | title = Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation | journal = J. Biol. Chem. | volume = 276 | issue = 14 | pages = 10715–21 | date = Apr 2001 | pmid = 11154691 | doi = 10.1074/jbc.M007846200 }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Strauss EC, Andrews NC, Higgs DR, Orkin SH | title = In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. | journal = Mol. Cell. Biol. | volume = 12 | issue = 5 | pages = 2135–42 | year = 1992 | pmid = 1569944 | pmc = 364385 | doi = }}
- {{cite journal | vauthors = Pischedda C, Cocco S, Melis A, Marini MG, Kan YW, Cao A, Moi P | title = Isolation of a differentially regulated splicing isoform of human NF-E2 | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 92 | issue = 8 | pages = 3511–5 | year = 1995 | pmid = 7724591 | pmc = 42197 | doi = 10.1073/pnas.92.8.3511 }}
- {{cite journal | vauthors = Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJ, Orkin SH | title = Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development | journal = Cell | volume = 81 | issue = 5 | pages = 695–704 | year = 1995 | pmid = 7774011 | doi = 10.1016/0092-8674(95)90531-6 }}
- {{cite journal | vauthors = Igarashi K, Kataoka K, Itoh K, Hayashi N, Nishizawa M, Yamamoto M | title = Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins | journal = Nature | volume = 367 | issue = 6463 | pages = 568–72 | year = 1994 | pmid = 8107826 | doi = 10.1038/367568a0 }}
- {{cite journal | vauthors = Chan JY, Han XL, Kan YW | title = Isolation of cDNA encoding the human NF-E2 protein | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 90 | issue = 23 | pages = 11366–70 | year = 1994 | pmid = 8248255 | pmc = 47983 | doi = 10.1073/pnas.90.23.11366 }}
- {{cite journal | vauthors = Toki T, Itoh J, Kitazawa J, Arai K, Hatakeyama K, Akasaka J, Igarashi K, Nomura N, Yokoyama M, Yamamoto M, Ito E | title = Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif | journal = Oncogene | volume = 14 | issue = 16 | pages = 1901–10 | year = 1997 | pmid = 9150357 | doi = 10.1038/sj.onc.1201024 }}
- {{cite journal | vauthors = Blank V, Kim MJ, Andrews NC | title = Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression | journal = Blood | volume = 89 | issue = 11 | pages = 3925–35 | year = 1997 | pmid = 9166829 | doi = }}
- {{cite journal | vauthors = Gavva NR, Gavva R, Ermekova K, Sudol M, Shen CJ | title = Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II | journal = J. Biol. Chem. | volume = 272 | issue = 39 | pages = 24105–8 | year = 1997 | pmid = 9305852 | doi = 10.1074/jbc.272.39.24105 }}
- {{cite journal | vauthors = Mosser EA, Kasanov JD, Forsberg EC, Kay BK, Ney PA, Bresnick EH | title = Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domains | journal = Biochemistry | volume = 37 | issue = 39 | pages = 13686–95 | year = 1998 | pmid = 9753456 | doi = 10.1021/bi981310l }}
- {{cite journal | vauthors = Hung HL, Kim AY, Hong W, Rakowski C, Blobel GA | title = Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation | journal = J. Biol. Chem. | volume = 276 | issue = 14 | pages = 10715–21 | year = 2001 | pmid = 11154691 | doi = 10.1074/jbc.M007846200 }}
- {{cite journal | vauthors = Gavva NR, Wen SC, Daftari P, Moniwa M, Yang WM, Yang-Feng LP, Seto E, Davie JR, Shen CK | title = NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor | journal = Genomics | volume = 79 | issue = 3 | pages = 423–31 | year = 2002 | pmid = 11863372 | doi = 10.1006/geno.2002.6714 }}
- {{cite journal | vauthors = Boulanger L, Sabatino DE, Wong EY, Cline AP, Garrett LJ, Garbarz M, Dhermy D, Bodine DM, Gallagher PG | title = Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins | journal = J. Biol. Chem. | volume = 277 | issue = 44 | pages = 41563–70 | year = 2003 | pmid = 12196550 | doi = 10.1074/jbc.M208184200 }}
- {{cite journal | vauthors = Marini MG, Asunis I, Chan K, Chan JY, Kan YW, Porcu L, Cao A, Moi P | title = Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation | journal = Blood Cells Mol. Dis. | volume = 29 | issue = 2 | pages = 145–58 | year = 2003 | pmid = 12490281 | doi = 10.1006/bcmd.2002.0550 }}
- {{cite journal | vauthors = Onishi Y, Kiyama R | title = Interaction of NF-E2 in the human beta-globin locus control region before chromatin remodeling | journal = J. Biol. Chem. | volume = 278 | issue = 10 | pages = 8163–71 | year = 2003 | pmid = 12509425 | doi = 10.1074/jbc.M209612200 }}
- {{cite journal | vauthors = Newman JR, Keating AE | title = Comprehensive identification of human bZIP interactions with coiled-coil arrays | journal = Science | volume = 300 | issue = 5628 | pages = 2097–101 | year = 2003 | pmid = 12805554 | doi = 10.1126/science.1084648 }}
- {{cite journal | vauthors = Chuen CK, Li K, Yang M, Fok TF, Li CK, Chui CM, Yuen PM | title = Interleukin-1beta up-regulates the expression of thrombopoietin and transcription factors c-Jun, c-Fos, GATA-1, and NF-E2 in megakaryocytic cells | journal = J. Lab. Clin. Med. | volume = 143 | issue = 2 | pages = 75–88 | year = 2004 | pmid = 14966463 | doi = 10.1016/j.lab.2003.09.006 }}
- {{cite journal|authorlink30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
{{refend}} External links - {{MeshName|NFE2+protein,+human}}
- {{FactorBook|NF-E2}}
{{NLM content}}{{Transcription factors|g1}}{{DEFAULTSORT:Nfe2}}{{gene-12-stub}} 2 : Transcription factors|Human proteins |