| 词条 | Niludipine |
| 释义 |
| verifiedrevid = 392775255 | ImageFile=File:Niludipine.svg | ImageSize=250px | PIN = Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | OtherNames = 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid bis(2-propoxyethyl) ester |Section1={{Chembox Identifiers | CASNo=22609-73-0 | PubChem= 89767 | SMILES=CCCOCCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOCCC)C)C | EINECS = 245-120-6 | ChemSpiderID = 81025 | InChI = 1/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3 | InChIKey = VZWXXKDFACOXNT-UHFFFAOYAS | StdInChI = 1S/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3 | StdInChIKey = VZWXXKDFACOXNT-UHFFFAOYSA-N | RTECS = | MeSHName = C019497 |Section2={{Chembox Properties | C=25 | H=34 | N=2 | O=8 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}Niludipine is a calcium channel blocker of the dihydropyridine class. It is a vasodilator that acts upon the coronary arteries of the heart-lung. It was found to produce a calcium antagonistic effect on the smooth muscle of hearts of canines and guinea pigs inhibiting myocardial oxidative metabolism.[1] References1. ^{{cite journal |last1=Hashimoto |first1=K |title=Effects of niludipine on the Cardiovascular system with a note on its Calcium-Antagonistic effects. |journal=Arzneimittel-Forschung |volume=29 |issue=9 |pages=1368–73 |url=https://europepmc.org/abstract/med/583243 | pmid = 583243|year=1979 }} {{Calcium channel blockers}}{{Biochem-stub}} 5 : Calcium channel blockers|Pyridines|Carboxylate esters|Ethers|Nitrobenzenes |
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