| 释义 |
- References
- Further reading
{{Underlinked|date=June 2016}}{{Infobox_gene}}NF-kappa-B-repressing factor is a protein that in humans is encoded by the NKRF gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.[3]
}}References1. ^{{cite journal | vauthors = Nourbakhsh M, Hauser H | title = Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB | journal = EMBO J | volume = 18 | issue = 22 | pages = 6415–25 |date=Jan 2000 | pmid = 10562553 | pmc = 1171704 | doi = 10.1093/emboj/18.22.6415 }}
2. ^{{cite web | title = Entrez Gene: NKRF NF-kappaB repressing factor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55922| accessdate = }}
3. ^{{cite web | title = Entrez Gene: NKRF NF-kappaB repressing factor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55922| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Frattini A, Faranda S, Bagnasco L, etal |title=Identification of a new member (ZNF183) of the Ring finger gene family in Xq24-25 |journal=Gene |volume=192 |issue= 2 |pages= 291–8 |year= 1997 |pmid= 9224902 |doi=10.1016/S0378-1119(97)00108-X }}
- {{cite journal |vauthors=Feng X, Guo Z, Nourbakhsh M, etal |title=Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 22 |pages= 14212–7 |year= 2002 |pmid= 12381793 |doi= 10.1073/pnas.212306199 | pmc=137863 }}
- {{cite journal |vauthors=Scherl A, Couté Y, Déon C, etal |title=Functional proteomic analysis of human nucleolus |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 | pmc=133617 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Jianfeng D, Feng J, Chaoneng J, etal |title=Cloning of the correct full length cDNA of NF-kappaB-repressing factor |journal=Mol. Cells |volume=16 |issue= 3 |pages= 397–401 |year= 2004 |pmid= 14744032 |doi= }}
- {{cite journal |vauthors=Niedick I, Froese N, Oumard A, etal |title=Nucleolar localization and mobility analysis of the NF-kappaB repressing factor NRF |journal=J. Cell Sci. |volume=117 |issue= Pt 16 |pages= 3447–58 |year= 2005 |pmid= 15226370 |doi= 10.1242/jcs.01129 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Dreikhausen U, Hiebenthal-Millow K, Bartels M, etal |title=NF-kappaB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor |journal=Mol. Cell. Biol. |volume=25 |issue= 17 |pages= 7473–83 |year= 2005 |pmid= 16107696 |doi= 10.1128/MCB.25.17.7473-7483.2005 | pmc=1190279 }}
- {{cite journal |vauthors=Fukuyama R, Ng KP, Cicek M, etal |title=Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells |journal=Mol. Carcinog. |volume=46 |issue= 5 |pages= 402–13 |year= 2007 |pmid= 17186550 |doi= 10.1002/mc.20288 }}
- {{cite journal |vauthors=Reboll MR, Oumard A, Gazdag AC, etal |title=NRF IRES activity is mediated by RNA binding protein JKTBP1 and a 14-nt RNA element |journal=RNA |volume=13 |issue= 8 |pages= 1328–40 |year= 2007 |pmid= 17592041 |doi= 10.1261/rna.545407 | pmc=1924892 }}
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