| 词条 | NS-398 |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 424846904 | Reference=[1] | ImageFile=NS-398.png | ImageSize=180px | ImageFile1 = NS-398 molecule spacefill.png | ImageAlt1 = Space-filling model of the NS-398 molecule | IUPACName=N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide | OtherNames= |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=123653-11-2 | PubChem=4553 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 73458 | SMILES=CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 4393 | InChI = 1/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | InChIKey = KTDZCOWXCWUPEO-UHFFFAOYAY | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = KTDZCOWXCWUPEO-UHFFFAOYSA-N |Section2={{Chembox Properties | C=13 | H=18 | N=2 | O=5 | S=1 | Appearance=Off-white solid | Density= | MeltingPt= | BoilingPt= | Solubility=Insoluble | SolubleOther = 5 mg/mL | Solvent = DMSO |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = | RPhrases = | SPhrases = {{S22}} {{S24/25}} }}NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.[2] See also
References1. ^NS-398 at Sigma-Aldrich {{Prostanoidergics}}{{Organic-compound-stub}}2. ^{{cite journal | journal = American Journal of Pathology | year = 2005 | volume = 167 | issue = 4 | pages = 1105–1117 | title = NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis |author1=Wei Shen |author2=Yong Li |author3=Ying Tang |author4=James Cummins |author5=Johnny Huard | pmid = 16192645 | pmc = 1603662 | doi = 10.1016/S0002-9440(10)61199-6}} 6 : COX-2 inhibitors|Nonsteroidal anti-inflammatory drugs|Nitrobenzenes|Sulfonamides|Phenol ethers|Cyclohexanes |
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