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词条 N-sulfoglucosamine-3-sulfatase
释义

  1. References

{{enzyme
| Name = N-sulfoglucosamine-3-sulfatase
| EC_number = 3.1.6.15
| CAS_number =
| IUBMB_EC_number = 3/1/6/15
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a N-sulfoglucosamine-3-sulfatase ({{EC number|3.1.6.15}}) is an enzyme that catalyzes the chemical reaction of cleaving off the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.[1][2]

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is N-sulfo-3-sulfoglucosamine 3-sulfohydrolase. This enzyme is also called chondroitinsulfatase. This enzyme participates in the degradtaion of glycan structures.

References

1. ^{{cite journal |vauthors=Bruce JS, McLean MW, Long WF, Williamson FB | year = 1985 | title = Flavobacterium heparinum 3-O-sulphatase for N-substituted glucosamine 3-O-sulphate | journal = Eur. J. Biochem. | volume = 148 | pages = 359–65 | pmid = 3987694 | doi = 10.1111/j.1432-1033.1985.tb08847.x | issue = 2 }}
2. ^{{cite journal | author = Leder IG | year = 1980 | title = A novel 3-O sulfatase from human urine acting on methyl-2-deoxy-2-sulfamino-alphs-D-glucopyranoside 3-sulfate | journal = Biochem. Biophys. Res. Commun. | volume = 94 | pages = 1183–9 | pmid = 7396957 | doi = 10.1016/0006-291X(80)90544-6 | issue = 4 }}
{{Esterases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{3.1-enzyme-stub}}

2 : EC 3.1.6|Enzymes of unknown structure

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